Nfkbia Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
MGI:104741

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nfkb1^tm1Bal/Nfkb1^tm1Bal Nfkbia^tm1Bal/Nfkbia^tm1Bal involves: 129S4/SvJae * C57BL/6J	postnatal lethality, complete penetrance	J:30058
Nfkbia^{tm1(Nfkbib)Brv}/Nfkbia^{tm1(Nfkbib)Brv} involves: 129S1/Sv * ICR	no abnormal phenotype detected	J:50029
Nfkbia^tm1Bal/Nfkbia^tm1Bal Nfkbie^tm1Syme/Nfkbie^tm1Syme involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2	abnormal B cell differentiation	J:88142
	abnormal T cell differentiation	J:88142
	decreased immature B cell number	J:88142
	decreased pre-B cell number	J:88142
	increased B cell apoptosis	J:88142
	increased T cell apoptosis	J:88142
	neonatal lethality, complete penetrance	J:88142

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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