Sez6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sez6
seizure related gene 6
MGI:104745

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sez6^tm1.1Sest/Sez6^tm1.1Sest involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal CNS synaptic transmission	J:132725
	abnormal dendrite morphology	J:132725
	abnormal excitatory postsynaptic currents	J:132725
	abnormal excitatory postsynaptic potential	J:132725
	abnormal locomotor behavior	J:132725
	abnormal neurite morphology	J:132725
	abnormal spatial learning	J:132725
	decreased locomotor activity	J:132725
	decreased susceptibility to pharmacologically induced seizures	J:132725
	decreased vertical activity	J:132725
	impaired coordination	J:132725
	impaired swimming	J:132725
Sez6^tm1Hta/Sez6^tm1Hta involves: 129 * C57BL	no abnormal phenotype detected	J:111556

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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