Nrcam Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nrcam
neuronal cell adhesion molecule
MGI:104750

38 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cntnap1^tm1Pele/Cntnap1^tm1Pele Nrcam^tm1Gmt/Nrcam^tm1Gmt involves: 129P2/OlaHsd * ICR	abnormal axon morphology	J:166099
	ataxia	J:166099
	decreased nerve conduction velocity	J:166099
	paralysis	J:166099
	postnatal lethality, complete penetrance	J:166099
Gars1^C201R/Gars1⁺ Nrcam^m1J/Nrcam^m1J involves: BALB/cAnN * C3H/HeH * C57BL/6J	abnormal axon morphology	J:240096
	abnormal innervation pattern to muscle	J:240096
	abnormal neuromuscular synapse morphology	J:240096
	decreased nerve conduction velocity	J:240096
	impaired coordination	J:240096
	muscle hypoplasia	J:240096
	tremors	J:240096
L1cam^tm1Sor/L1cam⁺ Nrcam^tm1Gmt/Nrcam^tm1Gmt involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster	postnatal lethality, incomplete penetrance	J:71828
L1cam^tm1Sor/Y Nrcam^tm1Gmt/Nrcam⁺ involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster	postnatal lethality, incomplete penetrance	J:71828
L1cam^tm1Sor/Y Nrcam^tm1Gmt/Nrcam^tm1Gmt involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster	abnormal cerebellar cortex morphology	J:71828
	abnormal cerebellar foliation	J:71828
	abnormal cerebellar granule layer morphology	J:71828
	abnormal cerebellum development	J:71828
	abnormal cerebellum external granule cell layer morphology	J:71828
	decreased body weight	J:71828
	postnatal lethality	J:71828
	small cerebellum	J:71828
Lpin1²⁰⁸⁸⁴/Lpin1²⁰⁸⁸⁴ Nrcam²⁰⁸⁸⁴/Nrcam²⁰⁸⁸⁴ involves: C57BL/6J	abnormal action potential	J:153042
	abnormal gait	J:153042
	abnormal myelin sheath morphology	J:153042
	abnormal nursing	J:153042
	abnormal sciatic nerve morphology	J:153042
	abnormal sexual interaction	J:153042
	decreased body weight	J:153042
	decreased grip strength	J:153042
	decreased joint mobility	J:153042
	decreased nerve conduction velocity	J:153042
	demyelination	J:153042
	hindlimb paralysis	J:153042
	limb grasping	J:153042
	paresis	J:153042
	skeletal muscle fiber atrophy	J:153042
Lpin1^fld/Lpin1^fld Nrcam²⁰⁸⁸⁴/Nrcam²⁰⁸⁸⁴ involves: BALB/cByJ * C57BL/6J	forelimb paresis	J:153042
	hindlimb paralysis	J:153042
	postnatal growth retardation	J:153042
	skeletal muscle fiber atrophy	J:153042
Nfasc^tm1.1Brp/Nfasc^tm1.1Brp Nrcam^tm1Gmt/Nrcam^tm1Gmt involves: 129P2/OlaHsd * 129S6/SvEvTac * ICR	abnormal axon morphology	J:166099
Nrcam^m1J/Nrcam^m1J Sh3tc2^m1J/Sh3tc2^m1J B6.Cg-Nrcam^m1J Sh3tc2^m1J/GrsrRwb	abnormal nerve conduction	J:240096
	abnormal neuromuscular synapse morphology	J:240096
	decreased nerve conduction velocity	J:240096
	heart block	J:240096
	muscular atrophy	J:240096
	paralysis	J:240096
	premature death	J:240096

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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