Gast Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gast
gastrin
MGI:104768

19 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gast^tm1(INS)Ez/Gast⁺ involves: 129S4/SvJae * C57BL/6	abnormal insulin secretion	J:99270
	improved glucose tolerance	J:99270
	increased circulating insulin level	J:99270
Gast^tm1Lcs/Gast⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal digestive secretion	J:77780
Gast^tm1Lcs/Gast^tm1Lcs involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal iron homeostasis	J:142455
	decreased circulating iron level	J:142455
	increased circulating unsaturated transferrin level	J:142455
Gast^tm1Lcs/Gast^tm1Lcs involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal digestive secretion	J:77780, J:97527
	abnormal digestive system physiology	J:97527
	abnormal gastric gland morphology	J:77780
	abnormal gastric parietal cell morphology	J:77780, J:107860
	abnormal stomach mucosa morphology	J:97527
	increased stomach tumor incidence	J:97527
	stomach inflammation	J:97527
Gast^tm1Psi/Gast^tm1Psi involves: C57BL/6J	abnormal colon morphology	J:77985
	increased incidence of tumors by chemical induction	J:77985
	increased physiological sensitivity to xenobiotic	J:77985
Gast^tm1Tcw/Gast^tm1Tcw involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal colon morphology	J:43358
	abnormal gastric chief cell morphology	J:43358
	abnormal gastric parietal cell morphology	J:43358
	abnormal mucous neck cell morphology	J:43358
	abnormal stomach mucosa morphology	J:43358
	increased stomach pH	J:43358

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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