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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Erbb4
erb-b2 receptor tyrosine kinase 4
MGI:104771
30 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Erbb2tm1Mll/Erbb2tm1Mll
Erbb4tm1Fej/Erbb4tm1Fej
Tg(Gabra6-cre)CWwis/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		normal nervous system phenotype J:145947
Erbb3tm2Cbm/Erbb3tm3Cbm
Erbb4tm1Fej/Erbb4tm1Fej
Cnptm1(cre)Kan/?
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal myelination J:145464
normal nervous system phenotype J:145464
postnatal lethality, complete penetrance J:145464
Erbb4tm1Grl/Erbb4tm1Grl
Tg(Myh6-ERBB4)HT2Gass/0
B6.Cg-Erbb4tm1Grl Tg(Myh6-ERBB4)HT2Gass 		abnormal long-term potentiation J:182690
normal behavior/neurological phenotype J:182690
decreased anxiety-related response J:182690
decreased prepulse inhibition J:182690
enhanced long-term potentiation J:182690
impaired contextual conditioning behavior J:182690
impaired cued conditioning behavior J:182690
increased locomotor activity J:182690
Erbb4tm1Grl/Erbb4tm1Grl
Tg(Myh6-ERBB4)HT2Gass/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal cerebellar granule layer morphology J:84403
abnormal cranial nerve morphology J:84403
abnormal cranial neural crest cell migration J:84403
abnormal mammary gland alveolus morphology J:84403
abnormal mammary gland development J:84403
abnormal mammary gland growth during pregnancy J:84403
abnormal pulmonary alveolar duct morphology J:132190
abnormal respiratory function J:132190
abnormal surfactant secretion J:132190
normal cardiovascular system phenotype J:84403
normal craniofacial phenotype J:84403
decreased pulmonary respiratory rate J:132190
hypolactation J:84403
impaired lung alveolus development J:132190
increased airway responsiveness J:132190
increased granulocyte number J:132190
lung inflammation J:132190
normal nervous system phenotype J:145464
perinatal lethality, incomplete penetrance J:84403
thick pulmonary interalveolar septum J:132190
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory