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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cdk2
cyclin dependent kinase 2
MGI:104772
34 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdk2tm1.1Jro/Cdk2+
involves: 129S1/SvlmJ * 129S4/SvJaeSor * C57BL/6 		azoospermia J:183801
reduced male fertility J:183801
normal reproductive system phenotype J:183801
testicular atrophy J:183801
Cdk2tm1.1Jro/Cdk2tm1.1Jro
involves: 129S1/SvlmJ * 129S4/SvJaeSor * C57BL/6 		normal cellular phenotype J:183801
decreased body weight J:183801
prenatal lethality, incomplete penetrance J:183801
Cdk2tm1Kald/Cdk2tm1Kald
involves: 129S1/Sv 		abnormal male meiosis J:141249
decreased hepatocyte proliferation J:141249
infertility J:141249
Cdk2tm1Kald/Cdk2tm1Kald
involves: 129S1/Sv * C57BL/6 		abnormal cell cycle J:86203
abnormal male meiosis J:86203
abnormal oogenesis J:86203
abnormal ovary morphology J:86203
abnormal spermatogenesis J:86203
absent oocytes J:86203
absent primordial ovarian follicles J:86203
azoospermia J:86203
decreased body size J:86203
female infertility J:86203
male infertility J:86203
ovary atrophy J:86203
preweaning lethality, incomplete penetrance J:86203
small seminiferous tubules J:86203
small testis J:86203
uterus atrophy J:86203
Cdk2tm1Sgo/Cdk2tm1Sgo
involves: 129/Sv * CD-1 		abnormal female reproductive system morphology J:85230
abnormal fertility/fecundity J:85230
abnormal gametogenesis J:85230
abnormal male reproductive system morphology J:85230
abnormal meiosis J:85230
abnormal oocyte morphology J:85230
abnormal seminiferous tubule morphology J:85230
abnormal spermiogenesis J:85230
absent corpus luteum J:85230
absent ovarian follicles J:85230
infertility J:85230
ovary atrophy J:85230
testicular atrophy J:85230
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory