Runx1t1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Runx1t1
RUNX1 translocation partner 1
MGI:104793

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Runx1t1^{tm1b(EUCOMM)Hmgu}/Runx1t1⁺ C57BL/6N-Runx1t1^{tm1b(EUCOMM)Hmgu}/H	increased circulating triglyceride level	J:211773
Runx1t1^{tm1b(EUCOMM)Hmgu}/Runx1t1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Runx1t1^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, complete penetrance	J:211773
Runx1t1^tm1Buch/Runx1t1^tm1Buch involves: 129P2/OlaHsd	no abnormal phenotype detected	J:68499
Runx1t1^tm1Fc/Runx1t1⁺ involves: 129S/SvEv * C57BL/6	absent midgut	J:70590
Runx1t1^tm1Fc/Runx1t1^tm1Fc involves: 129S/SvEv * C57BL/6	abnormal duodenum morphology	J:70590
	abnormal intestinal epithelium morphology	J:70590
	abnormal intestine morphology	J:70590
	abnormal rectum morphology	J:70590
	abnormal small intestinal villus morphology	J:70590
	absent gastric milk in neonates	J:70590
	absent midgut	J:70590
	decreased body weight	J:70590
	male infertility	J:70590
	neonatal lethality, incomplete penetrance	J:70590
	omphalocele	J:70590
	pallor	J:70590
	postnatal growth retardation	J:70590
	postnatal lethality, incomplete penetrance	J:70590
	premature death	J:70590
	rectal hemorrhage	J:70590

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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