Lta Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lta
lymphotoxin A
MGI:104797

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lta^tm1Dch/Lta^tm1Dch Rorc^tm2Litt/Rorc⁺ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal gut-associated lymphoid tissue morphology	J:91566
Lta^tm1Dch/Lta^tm1Dch Tg(Igk-Lta/Ltb)4Cys/0 involves: 129S2/SvPas * C57BL/6J * DBA/2J	abnormal lymph organ development	J:73100
	abnormal spleen morphology	J:73100
	normal immune system phenotype	J:73100
Lta^tm1Dch/Lta^tm1Dch Tg(Ins2-Cxcl13)1Cys/0 involves: 129S2/SvPas * C57BL/6 * DBA/2	abnormal pancreatic islet morphology	J:110548
Lta^tm1Dch/Lta^tm1Dch Tnfsf14^tm1Lpc/Tnfsf14^tm1Lpc involves: 129S2/SvPas * 129X1/SvJ	abnormal lymphocyte morphology	J:173115
	abnormal thymus epithelium morphology	J:173115
	small thymus medulla	J:173115
Ltb/Tnf/Lta^tm1Dvk/Ltb/Tnf/Lta^tm1Dvk Mertk^nmf12/Mertk^nmf12 involves: C57BL/6J	abnormal retina morphology	J:175587
	retina photoreceptor degeneration	J:175587
	thin retina inner nuclear layer	J:175587
	thin retina outer nuclear layer	J:175587
Tg(Igk-Lta/Ltb)4Cys/0 involves: C57BL/6J * DBA/2J	abnormal B cell morphology	J:73100
Tg(Igk-Lta/Ltb)10Cys/0 involves: C57BL/6J * DBA/2J	abnormal B cell morphology	J:73100

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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