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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ier3
immediate early response 3
MGI:104814
23 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ier3tm1Mxw/Ier3tm1Mxw
involves: 129 * C57BL/6
abnormal CD4-positive, alpha-beta T cell physiology J:157504
abnormal interleukin level J:157504
abnormal macrophage physiology J:157504
abnormal response to infection J:157504
abnormal tumor necrosis factor level J:157504
abnormal tumor necrosis factor secretion J:157504
decreased regulatory T cell number J:157504
decreased vasodilation J:157504
delayed wound healing J:157504
impaired macrophage phagocytosis J:157504
increased granulocyte number J:157504
increased neutrophil cell number J:157504
increased susceptibility to parasitic infection J:157504
increased systemic arterial blood pressure J:157504
Ier3tm1Mxw/Ier3tm1Mxw
involves: C57BL/6
abnormal intestine physiology J:194587
abnormal physiological response to xenobiotic J:194587
decreased incidence of tumors by chemical induction J:194587
decreased susceptibility to induced colitis J:194587
increased T-helper 17 cell number J:194587
Ier3tm1Raku/Ier3tm1Raku
involves: 129S6/SvEvTac
decreased heart left ventricle muscle contractility J:131099
heart left ventricle hypertrophy J:131099
increased heart rate J:131099
increased myocardial fiber size J:131099
increased systemic arterial blood pressure J:131099

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory