Lbx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lbx1
ladybird homeobox 1
MGI:104867

41 phenotypes from 5 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lbx1^em1Mwil/Lbx1^em1Mwil Not Specified	abnormal dorsal interneuron 3 morphology	J:319391
	abnormal dorsal interneuron 4 morphology	J:319391
	abnormal dorsal interneuron 5 morphology	J:319391
	abnormal semilunar valve morphology	J:319391
	abnormal spinal cord dorsal horn morphology	J:319391
	abnormal spinal cord morphology	J:319391
	decreased motor neuron number	J:319391
	decreased neuron number	J:319391
	increased heart atrium size	J:319391
	increased heart left ventricle wall thickness	J:319391
	normal limbs/digits/tail phenotype	J:319391
	perinatal lethality, complete penetrance	J:319391
	short tibia	J:319391
	short vertebral column	J:319391
	small vertebrae	J:319391
Lbx1^tm1.1Khan/Lbx1^tm1.1Khan involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj	no abnormal phenotype detected	J:178868
Lbx1^tm1.1Khan/Lbx1^tm1.1Khan Myf5^tm3(cre)Sor/Myf5⁺ involves: 129S4/SvJaeSor * C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj	abnormal muscle precursor cell migration	J:178868
	abnormal skeletal muscle morphology	J:178868
	decreased body size	J:178868
Lbx1^tm1.1Khan/Lbx1^tm1.1Khan Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 CBA	abnormal skeletal muscle morphology	J:178868
Lbx1^tm1Gld/Lbx1^tm1Gld involves: 129S1/Sv	abnormal GABAergic neuron morphology	J:102513
	abnormal glutaminergic neuron morphology	J:102513
	abnormal skeletal muscle morphology	J:98439
	normal muscle phenotype	J:98439
Lbx1^tm1Gld/Lbx1^tm1Gld involves: 129S1/Sv * C57BL/6	abnormal forelimb morphology	J:56498
	abnormal hindlimb morphology	J:56498
	abnormal limb muscle morphology	J:56498
	abnormal muscle precursor cell migration	J:56498
	abnormal myogenesis	J:56498
	absent hypaxial muscle	J:56498
	decreased skeletal muscle mass	J:56498
	normal muscle phenotype	J:56498
	perinatal lethality, complete penetrance	J:56498
Lbx1^tm1Khan/Lbx1^tm1Khan involves: C57BL/6NCrlj * CBA/JNCrlj	neonatal lethality, complete penetrance	J:178868
Lbx1^tm1Thbr/Lbx1^tm1Thbr involves: 129S4/SvJae	abnormal coronary vessel morphology	J:109334
	abnormal forelimb morphology	J:57891
	abnormal heart development	J:109334
	abnormal heart looping	J:109334
	abnormal hindlimb morphology	J:57891
	abnormal limb muscle morphology	J:57891
	abnormal muscle precursor cell migration	J:57891
	embryonic growth arrest	J:109334
	embryonic lethality during organogenesis, incomplete penetrance	J:109334
	forelimb paralysis	J:57891
	hindlimb paralysis	J:57891
	normal muscle phenotype	J:57891
	thick interventricular septum	J:109334
	thick ventricular wall	J:109334
Lbx1^tm1Thbr/Lbx1^tm1Thbr involves: 129S4/SvJae * C57BL/6	abnormal dorsal spinal root morphology	J:78622
	abnormal neural tube morphology	J:78622
	abnormal spinal cord dorsal horn morphology	J:78622
	normal nervous system phenotype	J:78622

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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