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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gpx1
glutathione peroxidase 1
MGI:104887
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gpx1tm1Ysh/Gpx1+
Gpx2tm2Coh/Gpx2tm2Coh
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		diarrhea J:71506
intestinal inflammation J:71506
perianal ulcer J:71506
premature death J:71506
Gpx1tm1Ysh/Gpx1tm1Ysh
Gpx2tm2Coh/Gpx2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		diarrhea J:71506
intestinal inflammation J:71506
Gpx1tm1Ysh/Gpx1tm1Ysh
Gpx2tm2Coh/Gpx2tm2Coh
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal digestive system physiology J:71506
abnormal enzyme/coenzyme activity J:71506
abnormal enzyme/coenzyme level J:71506
cachexia J:71506
colitis J:71506
crypts of Lieberkuhn abscesses J:71506
decreased body temperature J:71506
decreased body weight J:71506
diarrhea J:71506
intestinal edema J:71506
intestinal inflammation J:71506
perianal ulcer J:71506
postnatal growth retardation J:71506
premature death J:71506
small intestinal inflammation J:71506
Gpx1tm1Ysh/Gpx1tm1Ysh
Gpx3tm1Hjco/Gpx3tm1Hjco
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased glutathione peroxidase activity J:159745
normal homeostasis/metabolism phenotype J:159745
Gpx1tm1Ysh/Gpx1tm1Ysh
Prkntm1Shn/Prkntm1Shn
Park7tm1Shn/Park7tm1Shn
B6.Cg-Park7tm1Shn Gpx1tm1Ysh Prkntm1Shn 		impaired coordination J:202221
increased dopamine level J:202221
increased serotonin level J:202221
Gpx1tm1Ysh/Gpx1tm1Ysh
SordC57BL/Lia/SordC57BL/Lia
involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA 		cataract J:142446
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory