Gpcpd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gpcpd1
glycerophosphocholine phosphodiesterase 1
MGI:104898

19 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gpcpd1^em1(IMPC)Tcp/Gpcpd1⁺ C57BL/6N-Gpcpd1^em1(IMPC)Tcp/Tcp	abnormal cholesterol homeostasis	J:211773
	abnormal skin morphology	J:211773
	abnormal sternum morphology	J:211773
	decreased circulating calcium level	J:211773
	decreased circulating creatinine level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased prepulse inhibition	J:211773
	enlarged lymph nodes	J:211773
Gpcpd1^em1(IMPC)Tcp/Gpcpd1^em1(IMPC)Tcp C57BL/6N-Gpcpd1^em1(IMPC)Tcp/Tcp	preweaning lethality, complete penetrance	J:211773
Gpcpd1^{tm1c(EUCOMM)Hmgu}/Gpcpd1^{tm1c(EUCOMM)Hmgu} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	normal homeostasis/metabolism phenotype	J:345630
Gpcpd1^{tm1c(EUCOMM)Hmgu}/Gpcpd1^{tm1c(EUCOMM)Hmgu} Tg(Ckmm-cre)5Khn/0 involves: C57BL/6J * C57BL/6N * FVB	abnormal muscle glycogen level	J:345630
	normal homeostasis/metabolism phenotype	J:345630
	hyperglycemia	J:345630
	impaired glucose tolerance	J:345630
	increased cardiac muscle cell glucose uptake	J:345630
	increased glycerophosphocholine level	J:345630
	increased insulin secretion	J:345630
	increased muscle cell glucose uptake	J:345630
	normal muscle phenotype	J:345630
Gpcpd1^{tm1c(EUCOMM)Hmgu}/Gpcpd1^{tm1c(EUCOMM)Hmgu} Tg(Fabp4-cre)1Rev/0 involves: C57BL/6J * C57BL/6N	homeostasis/metabolism phenotype	J:345630
Gpcpd1^{tm1c(EUCOMM)Hmgu}/Gpcpd1^{tm1c(EUCOMM)Hmgu} Tg(Ucp1-cre)1Evdr/0 involves: C57BL/6J * C57BL/6N * FVB	homeostasis/metabolism phenotype	J:345630

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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