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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ddx6
DEAD-box helicase 6
MGI:104976
29 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ddx6em1(IMPC)Mbp/Ddx6+
C57BL/6N-Ddx6em1(IMPC)Mbp/Ucd 		abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal neural tube morphology J:211773
abnormal skin morphology J:211773
decreased startle reflex J:211773
increased circulating total protein level J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
Ddx6em1(IMPC)Mbp/Ddx6em1(IMPC)Mbp
C57BL/6N-Ddx6em1(IMPC)Mbp/Ucd 		abnormal embryo turning J:211773
embryonic lethality prior to organogenesis J:211773
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Ddx6em1.1Ysa/Ddx6em1.1Ysa
Tg(Ddx4-cre)1Dcas/0
involves: 129S4/SvJaeSor * C57BL/6NCrlj * CBA/JNCrlj * FVB 		abnormal ovarian follicle morphology J:282136
abnormal ovary morphology J:282136
abnormal primordial ovarian follicle morphology J:282136
absent oocytes J:282136
decreased primary ovarian follicle number J:282136
decreased primordial ovarian follicle number J:282136
decreased secondary ovarian follicle number J:282136
decreased tertiary ovarian follicle number J:282136
female infertility J:282136
Ddx6em1.2Ysa/Ddx6em1.2Ysa
involves: C57BL/6NCrlj * CBA/JNCrlj 		abnormal embryo development J:329565
abnormal primitive streak formation J:329565
abnormal rostral-caudal axis patterning J:329565
caudal body truncation J:329565
decreased embryo size J:329565
embryonic growth retardation J:329565
embryonic lethality between implantation and placentation J:329565
embryonic lethality during organogenesis, complete penetrance J:329565
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory