Cyp7b1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cyp7b1
cytochrome P450, family 7, subfamily b, polypeptide 1
MGI:104978

12 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cyp7b1^{tm1b(EUCOMM)Wtsi}/Cyp7b1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Cyp7b1^{tm1b(EUCOMM)Wtsi}/Bay	decreased total retina thickness	J:211773
	impaired glucose tolerance	J:211773
Cyp7b1^tm1Lth/Cyp7b1^tm1Lth involves: 129P2/OlaHsd * C57BL/6	abnormal estrous cycle	J:96829
	abnormal mammary gland development	J:96829
	abnormal uterus development	J:96829
	absent estrous cycle	J:96829
	early sexual maturation	J:96829
	premature ovarian failure	J:96829
	uterus atrophy	J:96829
Cyp7b1^tm1Rus/Cyp7b1^tm1Rus involves: 129S/SvEv * C57BL/6J	abnormal cholesterol homeostasis	J:62587, J:62589
	decreased IgA level	J:170807
	normal homeostasis/metabolism phenotype	J:62587

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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