Ksr1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ksr1
kinase suppressor of ras 1
MGI:105051

25 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ksr1^tm1Kole/Ksr1^tm1Kole involves: 129S1/Sv * C57BL/6	abnormal cell physiology	J:84644
	abnormal hair cycle	J:84644
	abnormal hair follicle development	J:84644
	abnormal hair follicle inner root sheath morphology	J:84644
	abnormal hair follicle morphology	J:84644
	abnormal hair follicle orientation	J:84644
	abnormal hair shaft morphology	J:84644
	alopecia	J:84644
	blistering	J:84644
	decreased cell proliferation	J:84644
	decreased hair follicle number	J:84644
	normal neoplasm	J:84644
	sparse hair	J:84644
Ksr1^tm1Shaw/Ksr1^tm1Shaw involves: DBA/1LacJ	abnormal cell differentiation	J:100406
	decreased white fat cell number	J:100406
	increased fat cell size	J:100406
Ksr1^tm1Shaw/Ksr1^tm1Shaw Not Specified	abnormal learning/memory/conditioning	J:122941
	abnormal spatial reference memory	J:122941
	normal behavior/neurological phenotype	J:122941
	decreased susceptibility to induced arthritis	J:140520
	decreased T cell proliferation	J:75739
	impaired contextual conditioning behavior	J:122941
	impaired cued conditioning behavior	J:122941
	impaired synaptic plasticity	J:122941
	reduced long-term potentiation	J:122941

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24