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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnni2
troponin I, skeletal, fast 2
MGI:105070
29 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tnni2tm1.1(KOMP)Vlcg/Tnni2+
C57BL/6N-Tnni2tm1.1(KOMP)Vlcg/Ucd 		abnormal skin morphology J:211773
decreased circulating glucose level J:211773
decreased fasting circulating glucose level J:211773
decreased total body fat amount J:211773
Tnni2tm1.1(KOMP)Vlcg/Tnni2tm1.1(KOMP)Vlcg
C57BL/6N-Tnni2tm1.1(KOMP)Vlcg/Ucd 		preweaning lethality, complete penetrance J:211773
Tnni2tm1Sgao/Tnni2+
involves: 129 * ICR 		abnormal forelimb morphology J:228857
abnormal long bone epiphyseal plate morphology J:228857
abnormal long bone hypertrophic chondrocyte zone J:228857
decreased angiogenesis J:228857
decreased birth weight J:228857
decreased body size J:228857
decreased bone mineralization J:228857
decreased collagen level J:228857
decreased osteoblast cell number J:228857
decreased osteoblast proliferation J:228857
decreased trabecular bone mass J:228857
short forelimb J:228857
short hindlimb J:228857
short vertebral column J:228857
slow postnatal weight gain J:228857
Tnni2tm1Sgao/Tnni2tm1Sgao
involves: 129 * ICR 		abnormal epiphyseal plate morphology J:228857
abnormal forelimb morphology J:228857
abnormal intramembranous bone ossification J:228857
decreased birth weight J:228857
decreased body size J:228857
decreased bone mineralization J:228857
decreased width of hypertrophic chondrocyte zone J:228857
delayed endochondral bone ossification J:228857
postnatal lethality, incomplete penetrance J:228857
short humerus J:228857
short radius J:228857
short ulna J:228857
small scapula J:228857
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory