Satb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Satb1
special AT-rich sequence binding protein 1
MGI:105084

38 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Satb1^em1Zfa/Satb1^em1Zfa involves: C57BL/6	decreased common lymphocyte progenitor cell number	J:259392
Satb1^em1Zfa/Satb1^em1Zfa involves: C57BL/6	premature death	J:259392
Satb1^m1Anu/Satb1⁺ C57L/6JAnu-Satb1^m1Anu	abnormal CD4-positive, alpha beta T cell morphology	J:104190
Satb1^m1Anu/Satb1⁺ C57L/6JAnu-Satb1^m1Anu	abnormal CD8-positive, alpha beta T cell morphology	J:104190
Satb1^m1Anu/Satb1^m1Anu C57L/6JAnu-Satb1^m1Anu	abnormal CD4-positive, alpha beta T cell morphology	J:104190
Satb1^m1Anu/Satb1^m1Anu C57L/6JAnu-Satb1^m1Anu	abnormal CD8-positive, alpha beta T cell morphology	J:104190
Satb1^{tm1a(EUCOMM)Hmgu}/Satb1^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	abnormal brain interneuron morphology	J:196342
	normal nervous system phenotype	J:196342
	postnatal growth retardation	J:196342
	postnatal lethality, complete penetrance	J:196342
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1⁺ C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/Ics	abnormal auditory brainstem response	J:211773
	abnormal vitreous body morphology	J:211773
	increased circulating aspartate transaminase level	J:211773
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1⁺ C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/J	abnormal bone structure	J:211773
	hyperactivity	J:211773
	increased bone mineral content	J:211773
	increased exploration in new environment	J:211773
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/J	preweaning lethality, incomplete penetrance	J:211773
Satb1^tm1Kos/Satb1^tm1Kos involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:61085
	abnormal T cell proliferation	J:61085
	arrested T cell differentiation	J:61085
	decreased body size	J:61085
	decreased thymocyte number	J:61085
	delayed eyelid opening	J:61085
	limb grasping	J:61085
	postnatal growth retardation	J:61085
	postnatal lethality, complete penetrance	J:61085
	small lymph nodes	J:61085
	small spleen	J:61085
	small thymus	J:61085
Satb1^tm2Kos/Satb1^tm2Kos Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: C57BL/6 * C57BL/10 * CBA/Ca	abnormal renal glomerulus morphology	J:252606
	absent regulatory T cells	J:252606
	decreased salivation	J:252606
	increased anti-nuclear antigen antibody level	J:252606
	increased autoantibody level	J:252606
	increased susceptibility to autoimmune disorder	J:252606
	increased urine protein level	J:252606
	kidney inflammation	J:252606
	pancreas inflammation	J:252606
	premature death	J:252606
	salivary gland degeneration	J:252606
	salivary gland inflammation	J:252606

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24