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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ntn1
netrin 1
MGI:105088
28 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ntn1Gt(IRESBetageo)1Pgr/Ntn1Gt(IRESBetageo)1Pgr
involves: 129/Sv * C57BL/6 * NMRI 		abnormal brain commissure morphology J:57002
abnormal inner ear canal fusion J:57002
absent gastric milk in neonates J:57002
absent lateral semicircular canal J:57002
absent posterior semicircular canal J:57002
perinatal lethality, complete penetrance J:57002
Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
B6.129P2-Ntn1Gt(ST629)Byg 		normal hearing/vestibular/ear phenotype J:142510
normal nervous system phenotype J:109043
Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
involves: 129P2/OlaHsd 		abnormal mammary gland development J:109023
normal nervous system phenotype J:111725
perinatal lethality, complete penetrance J:109023
Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
involves: 129P2/OlaHsd * C57BL/6J 		abnormal corticospinal tract morphology J:80430
abnormal pyramidal decussation morphology J:80430
abnormal spinal cord dorsal column morphology J:80430
Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
involves: 129P2/OlaHsd * CD-1 		abnormal anterior commissure morphology J:37125
abnormal brain commissure morphology J:37125
abnormal locomotor coordination J:37125
abnormal pontine nuclei morphology J:37125
abnormal righting response J:37125
absent corpus callosum J:37125
absent gastric milk in neonates J:37125
absent hippocampal commissure J:37125
postnatal lethality, complete penetrance J:37125
Ntn1tm1.2Good/Ntn1tm1.2Good
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL 		abnormal palatal shelf fusion at midline J:277765
cleft secondary palate J:277765
coloboma J:277765
Ntn1tm1.2Tek/Ntn1tm1.2Tek
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * SJL 		abnormal axon guidance J:227232
abnormal dorsal spinal root morphology J:227232
abnormal spinal cord central canal morphology J:227232
abnormal spinal cord ependymal layer morphology J:227232
abnormal spinal cord ventral commissure morphology J:227232
lethality throughout fetal growth and development, complete penetrance J:227232
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory