Adcyap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adcyap1
adenylate cyclase activating polypeptide 1
MGI:105094

47 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adcyap1^tm1Aba/Adcyap1^tm1Aba either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * ICR)	decreased anxiety-related response	J:72576
	decreased grooming behavior	J:72576
	hyperactivity	J:72576
	increased exploration in new environment	J:72576
	increased vertical activity	J:72576
	postnatal lethality, incomplete penetrance	J:72576
	reduced female fertility	J:102717
	reduced fertility	J:72576
Adcyap1^tm1Aba/Adcyap1^tm1Aba involves: 129P2/OlaHsd * C57BL/6	abnormal cornea epithelium morphology	J:240066
	abnormal cornea morphology	J:240066
	cornea opacity	J:240066
	decreased tear production	J:240066
Adcyap1^tm1Aba/Adcyap1^tm1Aba involves: 129P2/OlaHsd * C57BL/6 * ICR	abnormal mating frequency	J:102717
	absent maternal crouching	J:102717
	decreased litter size	J:102717
	reduced female fertility	J:102717
Adcyap1^tm1Clw/Adcyap1^tm1Clw B6.129S4-Adcyap1^tm1Clw	abnormal regulatory T cell physiology	J:194151
	abnormal T cell activation	J:194151
	decreased dopaminergic neuron number	J:194151
	increased microglial cell activation	J:194151
	increased susceptibility to dopaminergic neuron neurotoxicity	J:194151
	increased T-helper 17 cell number	J:194151
Adcyap1^tm1Clw/Adcyap1^tm1Clw involves: 129S4/SvJae * C57BL/6	abnormal circadian behavior phase	J:94880
	increased locomotor activity	J:94880
	preweaning lethality, incomplete penetrance	J:94880
	shortened circadian behavior period	J:94880
Adcyap1^tm1Eid/Adcyap1^tm1Eid involves: 129S4/SvJae * C57BL/6	decreased adrenaline level	J:73702
	decreased circulating adrenaline level	J:73702
	hypoglycemia	J:73702
	normal nervous system phenotype	J:73702
Adcyap1^tm1Nms/Adcyap1^tm1Nms B6.129-Adcyap1^tm1Nms	abnormal sexual interaction	J:131950
	decreased circulating progesterone level	J:131950
	decreased circulating prolactin level	J:131950
	impaired embryo implantation	J:131950
	postnatal lethality, incomplete penetrance	J:131950
	reduced female fertility	J:131950
	slow postnatal weight gain	J:131950
Adcyap1^tm1Nms/Adcyap1^tm1Nms either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: C57BL/6)	abnormal skeletal muscle morphology	J:71968
	decreased liver glycogen level	J:71968
	decreased white adipose tissue amount	J:71968
	hypoglycemia	J:71968
	impaired adaptive thermogenesis	J:79468
	increased circulating cholesterol level	J:71968
	increased circulating corticosterone level	J:71968
	increased circulating free fatty acids level	J:71968
	increased circulating insulin level	J:71968
	increased circulating ketone body level	J:71968
	increased circulating triglyceride level	J:71968
	microvesicular hepatic steatosis	J:71968
	postnatal lethality, complete penetrance	J:71968, J:79468
	weight loss	J:71968

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