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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Efnb2
ephrin B2
MGI:105097
36 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Efnb1tm1.1Jwu/Efnb1tm1.1Jwu
Efnb2tm1.1Jwu/Efnb2tm1.1Jwu
Tg(Lck-cre)I540Jxm/0
B6.Cg-Efnb2tm1.1Jwu Efnb1tm1.1Jwu Tg(Lck-cre)I540Jxm 		abnormal bone marrow cell morphology/development J:178148
abnormal T cell differentiation J:178148
abnormal T-helper 1 cell differentiation J:178148
abnormal T-helper 17 cell differentiation J:178148
decreased CD4-positive, alpha-beta T cell number J:178148
decreased CD8-positive, alpha-beta T cell number J:178148
decreased DN4 thymocyte number J:178148
decreased double-positive T cell number J:178148
decreased spleen weight J:178148
decreased T cell number J:178148
decreased thymus weight J:178148
increased DN3 thymocyte number J:178148
increased double-negative T cell number J:178148
increased length of allograft survival J:178148
increased susceptibility to Riboviria infection J:178148
increased thymocyte apoptosis J:178148
small spleen J:178148
small thymus J:178148
spleen hypoplasia J:178148
thymus hypoplasia J:178148
Efnb1tm1.1Sor/Efnb1+
Efnb2tm2Sor/Efnb2+
involves: 129S4/SvJaeSor * C57BL/6J 		abnormal tracheal cartilage morphology J:143845
failure of eyelid fusion J:143845
small salivary gland J:143845
Efnb1tm1.1Sor/Efnb1+
Efnb2tm2Sor/Efnb2tm2Sor
involves: 129S4/SvJaeSor * C57BL/6 		abnormal coronal suture morphology J:115952
abnormal frontal bone morphology J:115952
Efnb1tm1.1Sor/Y
Efnb2tm2Sor/Efnb2+
involves: 129S4/SvJaeSor * C57BL/6J 		abnormal tracheal cartilage morphology J:143845
failure of eyelid fusion J:143845
small salivary gland J:143845
Efnb1tm1.1Sor/Y
Efnb2tm2Sor/Efnb2tm2Sor
involves: 129S4/SvJaeSor * C57BL/6 		normal craniofacial phenotype J:115952
Efnb2tm1And/Efnb2+
Rbpjtm1Kyo/Rbpjtm1Kyo
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal vascular development J:93125
Efnb2tm1Henk/Efnb2+
Ephb2tm2Paw/Ephb2tm2Paw
either: 129 or (involves: 129 * C57BL/6) or (involves: 129 * CD-1) 		hypospadia J:91491
Efnb2tm1Henk/Efnb2+
Ephb2tm2Paw/Ephb2tm2Paw
Ephb3tm1Kln/Ephb3+
either: 129 or (involves: 129 * C57BL/6) or (involves: 129 * CD-1) 		hypospadia J:91491
Efnb2tm1Henk/Efnb2+
Ephb2tm1Paw/Ephb2+
involves: 129S1/Sv * 129X1/SvJ * CD-1 		circling J:116671
Efnb2tm1Sor/Efnb2tm1Sor
129S4/SvJaeSor-Efnb2tm1Sor 		no abnormal phenotype detected J:143845
Efnb2tm5.1Kln/Efnb2tm5.1Kln
involves: C57BL/6 		abnormal afferent lymphatic vessel morphology J:95885
abnormal lymph circulation J:95885
abnormal lymphatic vessel morphology J:95885
chylothorax J:95885
postnatal lethality, complete penetrance J:95885
Efnb2tm5.1Kln/Efnb2tm5.1Kln
involves: CD-1 		abnormal lymphatic vessel morphology J:95885
chylothorax J:95885
premature death J:95885
Efnb2tm5.1Kln/Efnb2tm5.1Kln
Flt4tm1Ali/Flt4+
involves: C57BL/6 		abnormal afferent lymphatic vessel morphology J:95885
abnormal lymphatic vessel morphology J:95885
Efnb2tm6Kln/Efnb2tm6Kln
involves: C57BL/6 		abnormal lymph circulation J:95885
abnormal lymphatic vessel morphology J:95885
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory