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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mcm2
minichromosome maintenance complex component 2
MGI:105380
21 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mcm2Gt(AB0178)Wtsi/Mcm2+
involves: 129P2/OlaHsd * C3HeB/FeJ
abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2Gt(AB0178)Wtsi
involves: 129P2/OlaHsd * C3HeB/FeJ
prenatal lethality, complete penetrance J:165667
Mcm2tm1(cre/ERT2)Scpr/Mcm2tm1(cre/ERT2)Scpr
involves: 129S6/SvEvTac
abnormal breathing pattern J:141493
abnormal cell cycle J:141493
abnormal cell nucleus morphology J:141493
abnormal coat/hair pigmentation J:141493
abnormal erythrocyte morphology J:141493
abnormal postnatal subventricular zone morphology J:141493
abnormal small intestinal villus morphology J:141493
abnormal small intestine crypts of Lieberkuhn morphology J:141493
colon polyps J:141493
decreased locomotor activity J:141493
decreased total body fat amount J:141493
enlarged spleen J:141493
hunched posture J:141493
increased thymoma incidence J:141493
intestine polyps J:141493
muscle weakness J:141493
premature death J:141493
sparse hair J:141493
Mcm2tm2Scpr/Mcm2tm2Scpr
involves: 129S6/SvEvTac
no abnormal phenotype detected J:141950

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory