Cdkn2d Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdkn2d
cyclin dependent kinase inhibitor 2D
MGI:105387

18 phenotypes from 1 allele in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn2d^tm1Maro/Cdkn2d^tm1Maro involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CD-1	decreased cochlear inner hair cell number	J:118337
	decreased cochlear outer hair cell number	J:118337
Cdkn2d^tm1Maro/Cdkn2d^tm1Maro involves: 129P2/OlaHsd * C57BL/6	abnormal spermatogenesis	J:58959
	increased male germ cell apoptosis	J:58959
	multinucleated giant male germ cells	J:58959
	testicular atrophy	J:58959
Cdkn2d^tm1Maro/Cdkn2d^tm1Maro involves: 129X1/SvJ * C57BL/6	abnormal apoptosis	J:68829
	abnormal male meiosis	J:68829
	abnormal spermatogenesis	J:68829
	increased circulating follicle stimulating hormone level	J:68829
	oligozoospermia	J:68829
Cdkn2d^tm1Maro/Cdkn2d^tm1Maro involves: 129X1/SvJ * C57BL/6 * CD-1	abnormal cochlear hair cell physiology	J:83482
	absent distortion product otoacoustic emissions	J:83482
	cochlear hair cell degeneration	J:83482
	cochlear inner hair cell degeneration	J:83482
	cochlear outer hair cell degeneration	J:83482
	increased or absent threshold for auditory brainstem response	J:83482
	nonsyndromic hearing loss	J:83482
	sensorineural hearing loss	J:83482

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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