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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dmc1
DNA meiotic recombinase 1
MGI:105393
25 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dmc1em1Jcs/Dmc1em1Jcs
involves: C57BL/6J * FVB/NJ 		normal reproductive system phenotype J:267449
Dmc1em1Jcs/Dmc1tm1Jcs
involves: 129S4/SvJae * C57BL/6J * FVB/NJ 		normal reproductive system phenotype J:267449
Dmc1Mei11/Dmc1+
involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J 		abnormal female meiosis J:122037
abnormal ovarian follicle morphology J:122037
abnormal spermatocyte morphology J:122037
arrest of male meiosis J:122037
decreased oocyte number J:122037
male infertility J:122037
reduced female fertility J:122037
Dmc1Mei11/Dmc1+
involves: 129S4/SvJae * C57BL/6J 		abnormal female meiosis J:122037
abnormal ovarian follicle morphology J:122037
arrest of male meiosis J:122037
male infertility J:122037
Dmc1Mei11/Dmc1Mei11
involves: 129S4/SvJae * C57BL/6J 		abnormal seminiferous tubule morphology J:60747
abnormal spermiogenesis J:60747
decreased male germ cell number J:60747
male infertility J:60747
Dmc1tm1Jcs/Dmc1Mei11
involves: 129S4/SvJae * C57BL/6J 		abnormal ovarian follicle morphology J:122037
abnormal spermatocyte morphology J:122037
absent ovarian follicles J:122037
arrest of male meiosis J:122037
decreased oocyte number J:122037
female infertility J:122037
Dmc1tm1Jcs/Dmc1tm1Jcs
involves: 129S4/SvJae * C57BL/6 		abnormal male meiosis J:194067
Dmc1tm1Jcs/Dmc1tm1Jcs
involves: 129S4/SvJae * C57BL/6J 		abnormal female meiosis J:47308
abnormal gametogenesis J:47308
abnormal oogenesis J:47308
abnormal reproductive system morphology J:47308
abnormal spermatogenesis J:47308
absent oocytes J:47308, J:183982
absent ovarian follicles J:47308
arrest of male meiosis J:47308
azoospermia J:47308
decreased ovary weight J:47308
decreased testis weight J:47308
female infertility J:47308
infertility J:47308
male infertility J:47308
Dmc1tm1Tkm/Dmc1tm1Tkm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal gametogenesis J:47307
abnormal oogenesis J:47307
abnormal spermatogenesis J:47307
absent oocytes J:47307
absent ovarian follicles J:47307
arrest of male meiosis J:47307
azoospermia J:47307
infertility J:47307
male infertility J:47307
small ovary J:47307
small testis J:47307
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory