Cfb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cfb
complement factor B
MGI:105975

14 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cfb^{tm1.1(KOMP)Wtsi}/Cfb^{tm1.1(KOMP)Wtsi} C57BL/6N-Cfb^{tm1.1(KOMP)Wtsi}/J	decreased circulating phosphate level	J:211773
	increased erythrocyte cell number	J:211773
	increased fasting circulating glucose level	J:211773
	increased hematocrit	J:211773
	increased hemoglobin content	J:211773
Cfb^{tm1.1(KOMP)Wtsi}/Cfb^{tm1.1(KOMP)Wtsi} C57BL/6N-Cfb^{tm1.1(KOMP)Wtsi}/Ucd	abnormal kidney morphology	J:211773
	enlarged heart	J:211773
Cfb^tm1Hrc/Cfb^tm1Hrc involves: 129S/Sv	decreased susceptibility to Coronaviridae infection	J:286325
Cfb^tm1Hrc/Cfb^tm1Hrc involves: 129S/Sv	impaired complement classical pathway	J:130108
Cfb^tm1Hrc/Cfb^tm1Hrc involves: 129S/Sv * C57BL/6	abnormal complement pathway	J:42679
	impaired complement alternative pathway	J:42679
	reduced fertility	J:42679
Cfb^tm1Mbo/Cfb^tm1Mbo involves: 129/Sv * C57BL/6	increased susceptibility to bacterial infection	J:83712
Cfb^tm1Pkna/Cfb^tm1Pkna D1.129P2-Cfb^tm1Pkna	decreased susceptibility to induced arthritis	J:88872

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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