Tagln Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tagln
transgelin
MGI:106012

38 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Ddit3^tm1.1Irt/Ddit3^tm1.1Irt Tagln^tm2(cre)Yec/Tagln⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	decreased susceptibility to atherosclerosis	J:233223
	normal homeostasis/metabolism phenotype	J:233223
Irag1^tm2.1Jens/Irag1^tm2.1Jens Tagln^{tm2(PRKG1)Hfm}/Tagln^{tm2(PRKG1)Hfm} involves: 129S1/Sv * 129X1/SvJ	impaired muscle relaxation	J:175887
Msx1^tm1Bero/Msx1^tm1Bero Msx2^tm1Bero/Msx2^tm1Yvla Tagln^tm2(cre)Yec/Tagln⁺ involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac * NMRI	abnormal artery morphology	J:173525
	abnormal carotid artery morphology	J:173525
	abnormal vertebral artery morphology	J:173525
	intracranial aneurysm	J:173525
	intracranial hemorrhage	J:173525
	vascular smooth muscle hypoplasia	J:173525
Msx1^tm1Rem/Msx1^tm1Rem Msx2^tm1Yvla/Msx2^tm1Yvla Tagln^tm2(cre)Yec/Tagln⁺ involves: 129S2/SvPas * 129S6/SvEvTac * NMRI	abnormal carotid artery morphology	J:173525
	vascular smooth muscle hypoplasia	J:173525
Mylk^tm1Mzhu/Mylk^tm1Mzhu Tagln^{tm1(cre/ERT2)Feil}/? involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal defecation	J:141907
	abnormal digestive system physiology	J:141907
	abnormal gastrointestinal motility	J:141907
	abnormal intestinal peristalsis	J:141907
	abnormal intestinal smooth muscle morphology	J:141907
	abnormal intestine morphology	J:141907
	abnormal urinary bladder physiology	J:141907
	abnormal vertebral column morphology	J:141907
	decreased food intake	J:141907
	decreased systemic arterial blood pressure	J:141907
	decreased systemic arterial diastolic blood pressure	J:141907
	decreased systemic arterial systolic blood pressure	J:141907
	distended abdomen	J:141907
	distended ileum	J:141907
	distended jejunum	J:141907
	ischuria	J:141907
	premature death	J:141907
	small intestinal inflammation	J:141907
Pdcd10^tm1Wami/Pdcd10^tm1Wami Tagln^tm2(cre)Yec/Tagln⁺ involves: 129 * 129S6/SvEvTac * C57BL/6	normal cardiovascular system phenotype	J:171969
	normal mortality/aging	J:171969
Prkg1^tm2.1Naw/Prkg1^tm2.1Naw Tagln^{tm1(PRKG1)Hfm}/Tagln⁺ involves: 129S1/Sv 129X1/SvJ	decreased litter size	J:134928
	premature death	J:134928
	reduced female fertility	J:134928
Prkg1^tm2.1Naw/Prkg1^tm2.1Naw Tagln^{tm2(PRKG1)Hfm}/Tagln⁺ involves: 129S1/Sv 129X1/SvJ	decreased litter size	J:134928
	premature death	J:134928
	reduced female fertility	J:134928
Stk11^tm1.1Rdp/Stk11⁺ Tagln^{tm1(cre/ERT2)Feil}/Tagln⁺ involves: 129S/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	normal digestive/alimentary phenotype	J:134476
	gastrointestinal tract polyps	J:134476
	increased gastrointestinal tumor incidence	J:134476
	intestinal obstruction	J:134476
	premature death	J:134476
Stk11^tm1.1Rdp/Stk11^tm1.1Rdp Tagln^{tm1(cre/ERT2)Feil}/Tagln⁺ involves: 129S/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	gastrointestinal tract polyps	J:134476
	increased gastrointestinal tumor incidence	J:134476
Tagln^tm1Liw/Tagln⁺ Tbx18^tm1.1Mwmy/Tbx18^tm1.1Mwmy involves: 129 * C57BL/6J	abnormal coronary artery morphology	J:203805
	abnormal coronary vessel morphology	J:203805
	abnormal vascular smooth muscle morphology	J:203805

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24