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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
MGI:106018
25 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
St8sia2tm1Jxm/St8sia2tm1Jxm
St8sia4tm1.1Mifu/St8sia4tm1.1Mifu
involves: C57BL/6 		abnormal astrocyte morphology J:126687
abnormal brain interneuron morphology J:126687
abnormal brain morphology J:126687
abnormal cerebral cortex morphology J:126687
abnormal CNS glial cell morphology J:126687
abnormal corpus callosum morphology J:126687
abnormal diencephalon morphology J:126687
abnormal lateral ventricle morphology J:126687
abnormal motor capabilities/coordination/movement J:126687
abnormal neuron differentiation J:126687
abnormal postnatal subventricular zone morphology J:126687
abnormal rostral migratory stream morphology J:126687
decreased body size J:126687
decreased cerebral cortex pyramidal cell number J:126687
decreased striatum size J:126687
dilated lateral ventricle J:126687
ectopic cerebral cortex pyramidal cells J:126687
impaired neuronal migration J:126687
increased neuron apoptosis J:126687
loss of hippocampal neurons J:126687
postnatal lethality, complete penetrance J:126687
small cerebellum J:126687
small olfactory bulb J:126687
thin cerebral cortex J:126687
St8sia2tm1Jxm/St8sia2tm1Jxm
St8sia4tm1.1Mifu/St8sia4tm1.1Mifu
Tg(Thy1-YFP)HJrs/?
involves: C57BL/6 * CBA 		abnormal cerebral cortex pyramidal cell morphology J:126687
decreased cerebral cortex pyramidal cell number J:126687
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory