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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tfap2c
transcription factor AP-2, gamma
MGI:106032
29 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tfap2ctm1.1Hsc/Tfap2c+
involves: 129P2/OlaHsd 		decreased body size J:78934
Tfap2ctm1.1Hsc/Tfap2ctm1.1Hsc
involves: 129P2/OlaHsd 		abnormal trophoblast giant cell morphology J:78934
absent mesoderm J:78934
absent placental labyrinth J:78934
decreased embryo size J:78934
decreased trophoblast giant cell number J:78934
embryonic lethality during organogenesis, complete penetrance J:78934
small ectoplacental cone J:78934
Tfap2ctm1Hsc/Tfap2ctm1Hsc
involves: 129P2/OlaHsd * C57BL/6 		no abnormal phenotype detected J:75122
Tfap2ctm1Will/Tfap2ctm1Will
involves: 129S1/Sv * Black Swiss 		abnormal developmental patterning J:76369
abnormal dorsal-ventral axis patterning J:76369
abnormal embryonic tissue morphology J:76369
abnormal embryonic-extraembryonic boundary morphology J:76369
abnormal extraembryonic coelom morphology J:76369
abnormal extraembryonic ectoderm morphology J:76369
abnormal extraembryonic tissue morphology J:76369
abnormal mesoderm development J:76369
abnormal Reichert's membrane morphology J:76369
absent allantois J:76369
absent ectoplacental cavity J:76369
absent ectoplacental cone J:76369
absent mesoderm J:76369
decreased trophoblast giant cell number J:76369
disorganized embryonic tissue J:76369
disorganized extraembryonic tissue J:76369
embryonic growth retardation J:76369
embryonic lethality between implantation and somite formation, incomplete penetrance J:76369
embryonic lethality during organogenesis, complete penetrance J:76369
failure of primitive streak formation J:76369
failure to gastrulate J:76369
small ectoplacental cone J:76369
small embryonic epiblast J:76369
Tfap2ctm1Will/Tfap2ctm2Will
Tg(Zp3-cre)3Mrt/0
involves: 129S1/Sv * FVB/N 		normal embryo phenotype J:113442
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory