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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tfap2c
transcription factor AP-2, gamma
MGI:106032
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col1a1tm1(tetO-Tcfap2c)Hsc/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal circulating enzyme level J:174049
abnormal enterocyte proliferation J:174049
abnormal hepatocyte mitochondrial morphology J:174049
abnormal hepatocyte morphology J:174049
abnormal intestinal mucosa morphology J:174049
abnormal intestine development J:174049
abnormal pancreas physiology J:174049
abnormal small intestine morphology J:174049
decreased liver glycogen level J:174049
dehydration J:174049
normal immune system phenotype J:174049
increased circulating alanine transaminase level J:174049
increased circulating alkaline phosphatase level J:174049
increased circulating amylase level J:174049
increased circulating aspartate transaminase level J:174049
increased circulating lactate dehydrogenase level J:174049
increased hepatocyte apoptosis J:174049
increased hepatocyte proliferation J:174049
lethargy J:174049
liver failure J:174049
microvesicular hepatic steatosis J:174049
premature death J:174049
weight loss J:174049
Tfap2atm1Hsv/Tfap2atm2Will
Tfap2ctm1Will/Tfap2ctm2Will
Tg(Zp3-cre)3Mrt/0
involves: 129S1/Sv * FVB/N 		normal embryo phenotype J:113442
embryonic lethality between implantation and somite formation, incomplete penetrance J:113442
Tfap2atm2Will/Tfap2a+
Tfap2ctm1Will/Tfap2ctm2Will
Tg(Zp3-cre)3Mrt/0
involves: 129S1/Sv * FVB/N 		abnormal embryonic tissue morphology J:113442
abnormal extraembryonic tissue morphology J:113442
decreased embryo size J:113442
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory