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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Six4
sine oculis-related homeobox 4
MGI:106034
33 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Six1tm1Kwk/Six1tm1Kwk
Six4tm1Kwk/Six4tm1Kwk
involves: 129P2/OlaHsd 		abnormal dorsal root ganglion morphology J:103002
neonatal lethality, complete penetrance J:103002
Six1tm1Mair/Six1tm1Mair
Six4tm1Mair/Six4tm1Mair
either: 129/Sv-Six1tm1Mair Six4tm1Mair or B6N.129-Six1tm1Mair Six4tm1Mair 		abnormal forelimb morphology J:98519
abnormal genioglossus muscle morphology J:98519
abnormal hindlimb morphology J:98519
abnormal inner ear morphology J:98519
abnormal intrinsic tongue muscle morphology J:98519
abnormal muscle development J:98519
abnormal muscle precursor cell migration J:98519
abnormal skeletal muscle morphology J:98519
abnormal sternocostal joint morphology J:98519
absent eye muscles J:98519
absent hypaxial muscle J:98519
absent maxillary shelf J:98519
absent Meckel's cartilage J:98519
absent nasal bone J:98519
absent premaxilla J:98519
absent tongue muscles J:98519
absent tympanic ring J:98519
absent zygomatic bone J:98519
anotia J:98519
decreased embryo size J:98519
distended abdomen J:98519
exophthalmos J:98519
eyelids open at birth J:98519
muscle hypoplasia J:98519
perinatal lethality, complete penetrance J:98519
short mandible J:98519
short maxilla J:98519
short ribs J:98519
small orbits J:98519
small temporal bone J:98519
trunk curl J:98519
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory