Bcl11a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bcl11a
BCL11 transcription factor A
MGI:106190

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bcl11a^tm1Mbu/Bcl11a^tm1Mbu Epor^{tm1.1(EGFP/icre)Uk}/Epor⁺ Tg(HBB)8.1Gvs/0 involves: 129 * BALB/cJ * FVB/N	abnormal erythropoiesis	J:196405
	anemia	J:196405
	decreased erythrocyte cell number	J:196405
	decreased hematocrit	J:196405
	decreased hemoglobin content	J:196405
	increased circulating erythropoietin level	J:196405
	normal mortality/aging	J:196405
	reticulocytosis	J:196405
Bcl11a^tm1Mbu/Bcl11a^tm1Mbu Klf1^tm1Nimr/Klf1⁺ Epor^{tm1.1(EGFP/icre)Uk}/Epor⁺ Tg(HBB)8.1Gvs/0 involves: 129P2/OlaHsd * BALB/cJ * FVB/N	abnormal erythropoiesis	J:196405
	polychromatophilia	J:196405
Bcl11a^tm1Mbu/Bcl11a^tm1Mbu Klf1^tm1Nimr/Klf1⁺ Tg(HBB)8.1Gvs/0 involves: 129P2/OlaHsd * FVB	abnormal erythropoiesis	J:196405
	anemia	J:196405
	decreased erythrocyte cell number	J:196405
	decreased hematocrit	J:196405
	decreased hemoglobin content	J:196405
	decreased mean corpuscular hemoglobin	J:196405
	decreased mean corpuscular volume	J:196405
	increased circulating erythropoietin level	J:196405
	normal mortality/aging	J:196405
	polychromatophilia	J:196405
	reticulocytosis	J:196405
Bcl11a^tm1Pwt/Bcl11a^tm1Pwt Dnmt1^tm2Jae/Dnmt1⁺ Tg(Mx1-cre)1Cgn/0 involves: 129S4/SvJae * C57BL/6 * CBA	anemia	J:196140
	decreased erythrocyte cell number	J:196140
Bcl11a^tm1Pwt/Bcl11a^tm1Pwt Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ Tg(Mx1-cre)1Cgn/0 involves: 129X1/SvJ * C57BL/6 * CBA	abnormal dendritic cell differentiation	J:207383
	decreased B cell number	J:207383
	decreased dendritic cell number	J:207383
	decreased plasmacytoid dendritic cell number	J:207383
Bcl11a^tm1Pwt/Bcl11a^tm1Pwt Kdm1a^tm1.1Sho/Kdm1a⁺ Epor^{tm1.1(EGFP/icre)Uk}/Epor⁺ involves: 129 * BALB/cJ	anemia	J:196140
	decreased erythrocyte cell number	J:196140
	decreased hemoglobin content	J:196140
Bcl11a^tm1Pwt/Bcl11a^tm1Pwt Kdm1a^tm1.1Sho/Kdm1a^tm1.1Sho Tg(Mx1-cre)1Cgn/0 involves: 129 * C57BL/6 * CBA	decreased erythrocyte cell number	J:196140
	decreased hemoglobin content	J:196140
	decreased leukocyte cell number	J:196140
Bcl11a^tm2.1Peli/Bcl11a^tm2.1Peli Trp53^tm1Brn/Trp53^tm1Brn Gt(ROSA)26Sor^{tm2(cre/ERT2)Brn}/Gt(ROSA)26Sor⁺ involves: 129P2/OlaHsd * 129S1/Sv	abnormal hematopoietic stem cell physiology	J:194616
	decreased hematopoietic stem cell number	J:194616
	normal hematopoietic system phenotype	J:194616
	normal immune system phenotype	J:194616

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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