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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dmbt1
deleted in malignant brain tumors 1
MGI:106210
15 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dmbt1tm1Janm/Dmbt1tm1Janm
involves: 129P2/OlaHsd * C57BL/6 		increased susceptibility to induced colitis J:130258
Dmbt1tm1Kumc/Dmbt1tm1Kumc
B6.129X1-Dmbt1tm1Kumc 		normal digestive/alimentary phenotype J:132597
Dmbt1tm1Kumc/Dmbt1tm1Kumc
involves: 129X1/SvJ * C57BL/6J 		normal digestive/alimentary phenotype J:132597
normal neoplasm J:132597
Dmbt1tm1Qaa/Dmbt1tm1Qaa
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * SWR) 		abnormal inner cell mass apoptosis J:93477
abnormal inner cell mass morphology J:93477
absent egg cylinders J:93477
absent inner cell mass J:93477
embryonic lethality between implantation and somite formation, complete penetrance J:93477
inner cell mass degeneration J:93477
Dmbt1tm2Qaa/Dmbt1tm2Qaa
Tg(ATP6V1B1-cre)45Rnel/0
involves: C57BL/6 * C57BL/6J * CBA 		abnormal kidney cortex morphology J:167156
decreased circulating bicarbonate level J:167156
normal hearing/vestibular/ear phenotype J:167156
increased urine pH J:167156
metabolic acidosis J:167156
renal tubular acidosis J:167156
Dmbt1tm2Qaa/Dmbt1tm2Qaa
Tg(Hoxb7-cre)5526Cmb/0
involves: C57BL/6 * FVB/N 		abnormal kidney cortex morphology J:167156
decreased circulating bicarbonate level J:167156
normal hearing/vestibular/ear phenotype J:167156
increased urine pH J:167156
metabolic acidosis J:167156
renal tubular acidosis J:167156
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory