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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cdc42
cell division cycle 42
MGI:106211
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arhgap33tm1.1Wbm/Arhgap33tm1.1Wbm
Cdc42tm1Brak/Cdc42+
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ 		abnormal parietal lobe morphology J:185948
Cdc42tm1.1Yizh/Cdc42+
Nkx2-5tm1Siz/Nkx2-5+
involves: 129S4/SvJaeSor 		decreased cardiac output J:174208
decreased cardiac stroke volume J:174208
decreased heart ventricle muscle contractility J:174208
prolonged P wave J:174208
prolonged QRS complex duration J:174208
prolonged QT interval J:174208
Cdc42tm1Brak/Cdc42+
Rab8atm1.1Aha/Rab8a+
Tg(Vil1-cre)997Gum/0
involves: C57BL/6J * SJL 		abnormal cellular glucose uptake J:184563
abnormal crypts of Lieberkuhn morphology J:184563
abnormal intestine physiology J:184563
abnormal Paneth cell morphology J:184563
intestinal edema J:184563
Cdc42tm1Brak/Cdc42tm1Brak
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Lgr5tm1(cre/ERT2)Cle/Lgr5+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 		abnormal crypts of Lieberkuhn morphology J:184563
abnormal intestinal epithelium morphology J:184563
abnormal small intestinal villus morphology J:184563
absent Paneth cells J:184563
increased small intestinal crypt cell apoptosis J:184563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory