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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Aqp5
aquaporin 5
MGI:106215
20 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Aqp5em1Cya/Aqp5em1Cya
involves: C57BL/6N 		abnormal cornea epithelium morphology J:326269
abnormal lacrimal gland morphology J:326269
decreased tear production J:326269
dry eyes J:326269
Aqp5tm1Amn/Aqp5tm1Amn
involves: 129X1/SvJ * Black Swiss 		abnormal fluid regulation J:82588
abnormal salivary gland physiology J:82588
normal behavior/neurological phenotype J:85609
decreased body weight J:82588
decreased lung compliance J:72954
decreased salivation J:82588
normal endocrine/exocrine gland phenotype J:82588
normal hearing/vestibular/ear phenotype J:85609
increased airway resistance J:72954
increased airway responsiveness J:72954
increased bronchoconstrictive response J:72954
normal mortality/aging J:82588
normal muscle phenotype J:72954
prenatal lethality, incomplete penetrance J:82588
Aqp5tm1Ask/Aqp5tm1Ask
involves: C57BL/6J 		abnormal salivary gland physiology J:56302
decreased salivation J:56302
postnatal growth retardation J:56302
prenatal lethality, incomplete penetrance J:56302
Aqp5tm1Ask/Aqp5tm1Ask
involves: C57BL/6J * CD-1 		normal hearing/vestibular/ear phenotype J:71154
normal vision/eye phenotype J:62579
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory