Six5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Six5
sine oculis-related homeobox 5
MGI:106220

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Six5^tm1Rdd/Six5⁺ 129S4/SvJae-Six5^tm1Rdd	abnormal testis morphology	J:91207
	increased circulating follicle stimulating hormone level	J:91207
	nuclear cataract	J:61881
	oligozoospermia	J:91207
	seminiferous tubule degeneration	J:91207
	small seminiferous tubules	J:91207
Six5^tm1Rdd/Six5⁺ involves: 129S4/SvJae * C57BL/6	cataract	J:61881
Six5^tm1Rdd/Six5^tm1Rdd 129S4/SvJae-Six5^tm1Rdd	abnormal spermatid morphology	J:91207
	abnormal spermatogenesis	J:91207
	abnormal spermiogenesis	J:91207
	abnormal testis morphology	J:91207
	azoospermia	J:91207
	decreased Sertoli cell number	J:91207
	increased circulating follicle stimulating hormone level	J:91207
	increased Leydig cell number	J:91207
	male infertility	J:91207
	nuclear cataract	J:61881
	seminiferous tubule degeneration	J:91207
	small seminiferous tubules	J:91207
	small testis	J:91207
Six5^tm1Rdd/Six5^tm1Rdd involves: 129S4/SvJae * C57BL/6	cataract	J:61881
Six5^tm1Tap/Six5⁺ involves: 129/Sv * C57BL/6	cataract	J:61882
Six5^tm1Tap/Six5^tm1Tap involves: 129/Sv * C57BL/6	cataract	J:61882
Six5^tm1Tap/Six5^tm1Tap involves: 129/Sv * C57BL/6	normal muscle phenotype	J:61882

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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