Vps25 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vps25
vacuolar protein sorting 25
MGI:106354

23 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vps25^m1Lis/Vps25^m1Lis involves: C3H * C57BL/6J	abnormal cell morphology	J:223082
	abnormal hindlimb zeugopod morphology	J:223082
	abnormal outer ear morphology	J:223082
	abnormal scapula morphology	J:223082
	increased apoptosis	J:223082
	increased cell proliferation	J:223082
	lethality throughout fetal growth and development, complete penetrance	J:223082
	mandible hypoplasia	J:223082
	polydactyly	J:223082
	preaxial polydactyly	J:223082
	scapular bone foramen	J:223082
	short limbs	J:223082
	short snout	J:223082
Vps25^m1Lis/Vps25^{tm1(KOMP)Vlcg} involves: C3H * C57BL/6J * C57BL/6NTac	fetal growth retardation	J:223082
	hemorrhage	J:223082
Vps25^{tm1(KOMP)Vlcg}/Vps25^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	embryonic lethality, complete penetrance	J:223082
Vps25^{tm1.1(KOMP)Vlcg}/Vps25⁺ C57BL/6N-Vps25^{tm1.1(KOMP)Vlcg}/Tcp	abnormal embryo size	J:211773
	decreased heart weight	J:211773
	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
Vps25^{tm1.1(KOMP)Vlcg}/Vps25^{tm1.1(KOMP)Vlcg} C57BL/6N-Vps25^{tm1.1(KOMP)Vlcg}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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