Ccdc92 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccdc92
coiled-coil domain containing 92
MGI:106485

36 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccdc92^{tm1a(KOMP)Mbp}/Ccdc92^{tm1a(KOMP)Mbp} C57BL/6N-Ccdc92^{tm1a(KOMP)Mbp}	abnormal brown adipose tissue thermogenesis	J:332421
	abnormal fat cell differentiation	J:332421
	abnormal white adipose tissue morphology	J:332421
	abnormal white adipose tissue physiology	J:332421
	decreased brown fat cell size	J:332421
	decreased circulating cholesterol level	J:332421
	decreased circulating interleukin-1 beta level	J:332421
	decreased circulating interleukin-18 level	J:332421
	decreased circulating LDL cholesterol level	J:332421
	decreased circulating leptin level	J:332421
	decreased circulating triglyceride level	J:332421
	decreased epididymal fat pad weight	J:332421
	decreased inflammatory response	J:332421
	decreased lipogenesis	J:332421
	decreased liver triglyceride level	J:332421
	decreased liver weight	J:332421
	decreased macrophage cell number	J:332421
	decreased mesenteric fat pad weight	J:332421
	decreased subcutaneous adipose tissue amount	J:332421
	decreased susceptibility to diet-induced hepatic steatosis	J:332421
	decreased susceptibility to diet-induced obesity	J:332421
	decreased white fat cell size	J:332421
	improved glucose tolerance	J:332421
	increased brown fat cell number	J:332421
	increased circulating adiponectin level	J:332421
	increased energy expenditure	J:332421
	increased insulin sensitivity	J:332421
	increased locomotor activity	J:332421
	increased oxygen consumption	J:332421
Ccdc92^{tm1a(KOMP)Mbp}/Ccdc92^{tm1a(KOMP)Mbp} C57BL/6NCrl-Ccdc92^{tm1a(KOMP)Mbp}/MbpMmucd	increased blood urea nitrogen level	J:211773
	increased bone mineral density	J:211773
	increased circulating serum albumin level	J:211773
Ccdc92^{tm1b(KOMP)Mbp}/Ccdc92^{tm1b(KOMP)Mbp} C57BL/6N-Ccdc92^{tm1b(KOMP)Mbp}/Ucd	abnormal auditory brainstem response	J:211773
	decreased brain weight	J:211773
	decreased circulating cholesterol level	J:211773
	decreased grip strength	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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