Tsg101 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tsg101
tumor susceptibility gene 101
MGI:106581

23 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Wap-Tsg101)4389Kuw/0 FVB/N-Tg(Wap-Tsg101)4389Kuw	abnormal mammary gland development	J:121475
	normal endocrine/exocrine gland phenotype	J:121475
	increased mammary adenocarcinoma incidence	J:121475
Tsg101^tm1.1Kuw/Tsg101⁺ Not Specified	normal neoplasm	J:80891
Tsg101^tm1.1Kuw/Tsg101^tm1.1Kuw Not Specified	embryonic lethality between implantation and somite formation, complete penetrance	J:80891
Tsg101^{tm1b(EUCOMM)Hmgu}/Tsg101⁺ C57BL/6N-Tsg101^{tm1b(EUCOMM)Hmgu}/Nju	abnormal kidney morphology	J:211773
	decreased locomotor activity	J:211773
Tsg101^{tm1b(EUCOMM)Hmgu}/Tsg101^{tm1b(EUCOMM)Hmgu} C57BL/6N-Tsg101^{tm1b(EUCOMM)Hmgu}/Nju	preweaning lethality, complete penetrance	J:211773
Tsg101^tm1Kuw/Tsg101^tm1Kuw Not Specified	no abnormal phenotype detected	J:80891
Tsg101^tm1Kuw/Tsg101^tm1Kuw Tg(Wap-cre)11738Mam/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal mammary gland growth during lactation	J:121475
Tsg101^tm1Kuw/Tsg101^tm1Kuw Tg(Wap-cre)11738Mam/0 Not Specified	abnormal lactation	J:80891
	abnormal mammary gland development	J:80891
	abnormal mammary gland growth during lactation	J:80891
	normal neoplasm	J:80891
Tsg101^tm1Kuw/Tsg101^tm1Kuw Tg(Wap-cre)11738Mam/0 Tg(Wap-Tsg101)4389Kuw/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	normal endocrine/exocrine gland phenotype	J:121475
Tsg101^tm1Mak/Tsg101^tm1Mak either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)	abnormal embryonic-extraembryonic boundary morphology	J:67553
	abnormal gastrulation	J:67553
	abnormal parietal endoderm morphology	J:67553
	abnormal visceral endoderm morphology	J:67553
	absent inner cell mass proliferation	J:67553
	absent mesoderm	J:67553
	decreased cell proliferation	J:67553
	decreased embryo size	J:67553
	decreased mitotic index	J:67553
	disorganized extraembryonic tissue	J:67553
	embryonic growth arrest	J:67553
	embryonic lethality between implantation and somite formation, complete penetrance	J:67553
	failure of primitive streak formation	J:67553

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24