Tsg101 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tsg101
tumor susceptibility gene 101
MGI:106581

23 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Wap-Tsg101)4389Kuw/0 FVB/N-Tg(Wap-Tsg101)4389Kuw	abnormal mammary gland development	J:121475
	normal endocrine/exocrine gland phenotype	J:121475
	increased mammary adenocarcinoma incidence	J:121475
Tsg101^tm1.1Kuw/Tsg101⁺ Not Specified	normal neoplasm	J:80891
Tsg101^tm1.1Kuw/Tsg101^tm1.1Kuw Not Specified	embryonic lethality between implantation and somite formation, complete penetrance	J:80891
Tsg101^{tm1b(EUCOMM)Hmgu}/Tsg101⁺ C57BL/6N-Tsg101^{tm1b(EUCOMM)Hmgu}/Nju	abnormal kidney morphology	J:211773
	decreased locomotor activity	J:211773
Tsg101^{tm1b(EUCOMM)Hmgu}/Tsg101^{tm1b(EUCOMM)Hmgu} C57BL/6N-Tsg101^{tm1b(EUCOMM)Hmgu}/Nju	preweaning lethality, complete penetrance	J:211773
Tsg101^tm1Kuw/Tsg101^tm1Kuw Not Specified	no abnormal phenotype detected	J:80891
Tsg101^tm1Kuw/Tsg101^tm1Kuw Tg(Wap-cre)11738Mam/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal mammary gland growth during lactation	J:121475
Tsg101^tm1Kuw/Tsg101^tm1Kuw Tg(Wap-cre)11738Mam/0 Not Specified	abnormal lactation	J:80891
	abnormal mammary gland development	J:80891
	abnormal mammary gland growth during lactation	J:80891
	normal neoplasm	J:80891
Tsg101^tm1Kuw/Tsg101^tm1Kuw Tg(Wap-cre)11738Mam/0 Tg(Wap-Tsg101)4389Kuw/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	normal endocrine/exocrine gland phenotype	J:121475
Tsg101^tm1Mak/Tsg101^tm1Mak either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)	abnormal embryonic-extraembryonic boundary morphology	J:67553
	abnormal gastrulation	J:67553
	abnormal parietal endoderm morphology	J:67553
	abnormal visceral endoderm morphology	J:67553
	absent inner cell mass proliferation	J:67553
	absent mesoderm	J:67553
	decreased cell proliferation	J:67553
	decreased embryo size	J:67553
	decreased mitotic index	J:67553
	disorganized extraembryonic tissue	J:67553
	embryonic growth arrest	J:67553
	embryonic lethality between implantation and somite formation, complete penetrance	J:67553
	failure of primitive streak formation	J:67553

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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