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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Neurod6
neurogenic differentiation 6
MGI:106593
66 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Afdntm1.1Lfr/Afdntm1.1Lfr
Neurod6tm1(cre)Kan/Neurod6+
involves: 129 * C57BL/6 * SJL 		abnormal excitatory postsynaptic potential J:179366
abnormal hippocampus CA1 region morphology J:179366
abnormal hippocampus pyramidal cell morphology J:179366
abnormal synapse morphology J:179366
ectopic hippocampus pyramidal cells J:179366
Arhgap33tm1.1Wbm/Arhgap33tm1.1Wbm
Cdc42tm1Brak/Cdc42+
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ 		abnormal parietal lobe morphology J:185948
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N 		decreased cerebral cortex cell number J:240674
Cnih2tm1.1Ran/Cnih2tm1.1Ran
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NTac 		normal nervous system phenotype J:197912
reduced AMPA-mediated synaptic currents J:197912
Cnr1tm1.2Ltz/Cnr1tm1.2Ltz
Neurod6tm1(cre)Kan/Neurod6+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6NCrl 		abnormal axon fasciculation J:171771
abnormal impulsive behavior control J:179495
abnormal nervous system development J:171771
abnormal response to novel object J:179495
increased susceptibility to pharmacologically induced seizures J:122066
Cnr1tm2Ltz/Cnr1tm2.1Ltz
Neurod6tm1(cre)Kan/Neurod6+
B6.Cg-Cnr1tm2Ltz/Cnr1tm2.1Ltz Neurod6tm1(cre)Kan 		abnormal cued conditioning behavior J:199647
normal behavior/neurological phenotype J:199647
decreased synaptic depression J:199647
increased susceptibility to xenobiotic induced morbidity/mortality J:199647
Crhr1tm2Wrst/Crhr1tm2Wrst
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J 		abnormal CNS synaptic transmission J:176339
normal behavior/neurological phenotype J:176339
decreased anxiety-related response J:176339
normal homeostasis/metabolism phenotype J:176339
hyperactivity J:176339
Cul3tm1Jdsr/Cul3+
Neurod6tm1(cre)Kan/Neurod6+
Tg(Thy1-EGFP)MJrs/0
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J * CBA 		abnormal response to social novelty J:292173
normal growth/size/body region phenotype J:292173
increased anxiety-related response J:292173
increased dendritic spine density J:292173
increased miniature excitatory postsynaptic current frequency J:292173
increased miniature inhibitory postsynaptic current frequency J:292173
increased thigmotaxis J:292173
normal mortality/aging J:292173
normal nervous system phenotype J:292173
normal reproductive system phenotype J:292173
Cul3tm1Jdsr/Cul3tm1Jdsr
Neurod6tm1(cre)Kan/Neurod6+
Tg(Thy1-EGFP)MJrs/0
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J * CBA 		abnormal hippocampus morphology J:292173
abnormal stratification in cerebral cortex J:292173
absent corpus callosum J:292173
decreased body size J:292173
decreased brain weight J:292173
preweaning lethality J:292173
thin cerebral cortex J:292173
Dab1tm1.1Mull/Dab1tm1.1Mull
Neurod6tm1(cre)Kan/Neurod6+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal cortical marginal zone morphology J:174747
abnormal neuronal migration J:174747
abnormal telencephalon development J:174747
absent subplate J:174747
Grin2btm1.1Jlbr/Grin2btm1.1Jlbr
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ 		abnormal suckling behavior J:178913
increased locomotor activity J:178913
social withdrawal J:178913
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Neurod6tm1(cre)Kan/Neurod6+
involves: 129P2/OlaHsd 		abnormal cerebral cortex morphology J:92789
neonatal lethality, complete penetrance J:92789
Itgb8tm1Lfr/Itgb8tm2Lfr
Neurod6tm1(cre)Kan/Neurod6+
involves: 129/Sv * 129X1/SvJ * C57BL/6 * SJL 		no abnormal phenotype detected J:102190
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		normal nervous system phenotype J:154611
Lmo4tm1Gng/Lmo4tm1Gng
Neurod6tm1(cre)Kan/?
involves: 129X1/SvJ 		disorganized barrel cortex J:111629
Mapttm2Arbr/Mapt+
Neurod6tm1(cre)Kan/Neurod6+
Trim67tm1.1Slgu/Trim67tm1.1Slgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased corpus callosum size J:266702
Nedd4tm3.1Bros/Nedd4tm3.1Bros
Neurod6tm1(cre)Kan/Neurod6+
involves: 129 * C57BL/6 * C57BL/6N * SJL 		abnormal cerebral hemisphere morphology J:164745
abnormal dendrite morphology J:164745
normal nervous system phenotype J:164745
thin cerebral cortex J:164745
Neurod1tm1Mjts/Neurod1tm1Mjts
Neurod6tm1Kan/Neurod6tm1Kan
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J 		abnormal hippocampus granule cell layer J:62118
abnormal nervous system morphology J:62118
abnormal nervous system physiology J:62118
abnormal neuron physiology J:62118
absent dentate gyrus J:62118
decreased brain size J:62118
impaired ability to fire action potentials J:62118
postnatal growth retardation J:62118
postnatal lethality, complete penetrance J:62118
Neurod6tm1(cre)Kan/Neurod6+
Prkg1tm2Naw/Prkg1tm2.1Naw
involves: 129S1/Sv * 129X1/SvJ 		normal behavior/neurological phenotype J:84444
normal cardiovascular system phenotype J:84444
normal digestive/alimentary phenotype J:84444
normal mortality/aging J:84444
normal nervous system phenotype J:84444
reduced long-term potentiation J:84444
Neurod6tm1(cre)Kan/Neurod6+
Pik3r4mbe/Pik3r4tm1.1Mpnd
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C3H/HeH * C57BL/6 		abnormal hippocampus pyramidal cell layer J:258027
abnormal hippocampus stratum oriens morphology J:258027
ectopic hippocampus pyramidal cells J:258027
Nrg1tm1Fej/Nrg1tm1Fej
Neurod6tm1(cre)Kan/?
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		normal nervous system phenotype J:145464
Plp1tm1c(EUCOMM)Wtsi/Y
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		normal nervous system phenotype J:245100
Smarcc2tm1.1Stoy/Smarcc2tm1.1Stoy
Neurod6tm1(cre)Kan/Neurod6+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal nervous system phenotype J:197141
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory