Myo5b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myo5b
myosin VB
MGI:106598

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myo5b^tm1.1Cle/Myo5b^tm1.1Cle Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * DBA/2	abnormal enterocyte morphology	J:227079
	abnormal intestinal epithelium morphology	J:227079
	abnormal small intestinal microvillus morphology	J:227079
	abnormal small intestinal villus morphology	J:227079
	dehydration	J:227079
	diarrhea	J:227079
	fused small intestinal villi	J:227079
	small intestinal villus atrophy	J:227079
	weight loss	J:227079
Myo5b^{tm1a(KOMP)Wtsi}/Myo5b^{tm1a(KOMP)Wtsi} C57BL/6N-Myo5b^{tm1a(KOMP)Wtsi}	abnormal enterocyte morphology	J:229427
	abnormal intestinal epithelium morphology	J:229427
	abnormal small intestinal microvillus morphology	J:229427
	decreased body weight	J:229427
	diarrhea	J:229427
	hypoglycemia	J:229427
	perinatal lethality, complete penetrance	J:229427
	wrinkled skin	J:229427

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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