Serpinb9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Serpinb9
serine (or cysteine) peptidase inhibitor, clade B, member 9
MGI:106603

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Serpinb9^{em1(IMPC)Ccpcz}/Serpinb9^{em1(IMPC)Ccpcz} C57BL/6NCrl-Serpinb9^{em1(IMPC)Ccpcz}/Ccpcz	abnormal bone structure	J:211773
	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	cornea opacity	J:211773
	decreased effector memory T-helper cell number	J:211773
	enlarged heart	J:211773
	increased airway resistance	J:211773
Serpinb9^tm1.1Pib/Serpinb9^tm1.1Pib involves: BALB/cJ * C57BL/6J	abnormal dendritic cell antigen presentation	J:252016
	abnormal immune system morphology	J:252016
	abnormal immune system physiology	J:252016
	decreased cytotoxic T cell apoptosis	J:252016
	normal immune system phenotype	J:252016
Serpinb9^tm1Arp/Serpinb9^tm1Arp involves: C57BL/6	abnormal CD8-positive, alpha-beta cytotoxic T cell morphology	J:113349
	abnormal cytotoxic T cell physiology	J:113349
	abnormal enzyme/coenzyme activity	J:113349
	abnormal enzyme/coenzyme level	J:113349
	decreased cytotoxic T cell cytolysis	J:113349
	increased apoptosis	J:113349
	increased susceptibility to Riboviria infection	J:113349

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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