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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Myo1e
myosin IE
MGI:106621
33 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Myo1eGt(ROSA)74Sor/Myo1eGt(ROSA)74Sor
involves: 129S4/SvJaeSor 		abnormal blood vessel morphology J:117491
anemia J:117491
decreased erythrocyte cell number J:117491
decreased hematocrit J:117491
decreased hemoglobin content J:117491
hemorrhage J:117491
polychromatophilia J:117491
prenatal lethality, incomplete penetrance J:117491
reticulocytosis J:117491
Myo1etm1.1Flv/Myo1etm1.1Flv
B6.129S6-Myo1etm1.1Flv 		abnormal podocyte foot process morphology J:188500
abnormal renal glomerulus basement membrane morphology J:188500
albuminuria J:188500
glomerulosclerosis J:188500
increased renal glomerulus basement membrane thickness J:188500
podocyte foot process effacement J:188500
podocyte microvillus transformation J:188500
renal cast J:188500
Myo1etm1.1Flv/Myo1etm1.1Flv
involves: 129S6/SvEvTac 		abnormal glomerular capillary morphology J:159163
abnormal podocyte foot process morphology J:159163
abnormal proximal convoluted tubule morphology J:159163
abnormal renal glomerular filtration rate J:159163
abnormal renal glomerulus morphology J:159163
abnormal urine homeostasis J:159163
albuminuria J:159163
enlarged kidney J:159163
expanded mesangial matrix J:159163
glomerulosclerosis J:159163
hematuria J:159163
hemoglobinuria J:159163
increased blood urea nitrogen level J:159163
increased kidney weight J:159163
increased renal glomerulus basement membrane thickness J:159163
increased urine protein level J:159163
leukocyturia J:159163
pale kidney J:159163
podocyte foot process effacement J:159163
proximal convoluted tubule brush border loss J:159163
renal cast J:159163
renal interstitial fibrosis J:159163
Myo1etm1Flv/Myo1etm1.1Flv
Tg(NPHS2-cre)295Lbh/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		albuminuria J:188500
glomerulosclerosis J:188500
renal cast J:188500
Myo1etm1Flv/Myo1etm1Flv
Tg(NPHS2-cre)295Lbh/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal podocyte foot process morphology J:188500
abnormal renal glomerulus basement membrane morphology J:188500
albuminuria J:188500
glomerulosclerosis J:188500
increased renal glomerulus basement membrane thickness J:188500
podocyte foot process effacement J:188500
renal cast J:188500
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory