Phox2a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Phox2a
paired-like homeobox 2a
MGI:106633

39 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Phox2a/Inppl1^tm1Ssch/Phox2a⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal glycogen homeostasis	J:96443
	decreased body weight	J:96443
	improved glucose tolerance	J:96443
Phox2a/Inppl1^tm1Ssch/Phox2a/Inppl1^tm1Ssch involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal gluconeogenesis	J:96443
	cyanosis	J:96443
	decreased circulating insulin level	J:96443
	hypoglycemia	J:96443
	increased insulin sensitivity	J:96443
	lethargy	J:96443
	postnatal growth retardation	J:96443
	postnatal lethality, complete penetrance	J:96443
	respiratory distress	J:96443
Phox2a^{tm1(Phox2b)Mist}/Phox2a^{tm1(Phox2b)Mist} involves: 129S2/SvPas	abnormal oculomotor nerve morphology	J:126634
	abnormal trochlear nerve morphology	J:126634
	normal mortality/aging	J:126634
	normal nervous system phenotype	J:126634
Phox2a^tm1.1Sgu/Phox2a^tm1.1Sgu involves: 129P2/OlaHsd * C57BL/6	abnormal autonomic nervous system morphology	J:63720
	abnormal cranial ganglia morphology	J:63720
	abnormal facial nerve morphology	J:63720
	abnormal locus ceruleus morphology	J:63720
	abnormal otic ganglion morphology	J:63720
	abnormal parasympathetic ganglion morphology	J:63720
	abnormal pterygopalatine ganglion morphology	J:63720
	abnormal respiration	J:89905
	decreased pulmonary respiratory rate	J:89905
	small geniculate ganglion	J:63720
	small nodose ganglion	J:63720
	small petrosal ganglion	J:63720
	small submandibular ganglion	J:63720
	small superior cervical ganglion	J:63720
	small trigeminal ganglion	J:63720
Phox2a^tm1.1Sgu/Phox2a^tm1.1Sgu involves: 129P2/OlaHsd * C57BL/6J	abnormal neuron differentiation	J:175535
	decreased motor neuron number	J:175535
	increased neuron number	J:175535
Phox2a^tm1Jbr/Phox2a⁺ involves: 129P2/OlaHsd * C57BL/6	increased pulmonary respiratory rate	J:121653
	increased pulmonary ventilation	J:121653
	increased tidal volume	J:121653
Phox2a^tm1Jbr/Phox2a^tm1Jbr involves: 129P2/OlaHsd	abnormal facial nerve morphology	J:157532
	abnormal pterygopalatine ganglion morphology	J:157532
	abnormal sublingual ganglion morphology	J:157532
	abnormal submandibular ganglion morphology	J:157532
Phox2a^tm1Jbr/Phox2a^tm1Jbr involves: 129P2/OlaHsd * C57BL/6	abnormal autonomic nervous system morphology	J:39084
	abnormal cranial ganglia morphology	J:39084
	abnormal locus ceruleus morphology	J:39084
	abnormal otic ganglion morphology	J:39084
	abnormal parasympathetic ganglion morphology	J:39084
	abnormal pterygopalatine ganglion morphology	J:39084
	small geniculate ganglion	J:39084
	small nodose ganglion	J:39084
	small petrosal ganglion	J:39084
	small submandibular ganglion	J:39084
	small superior cervical ganglion	J:39084
Phox2a^tm2.1Jbr/Phox2a^tm2.1Jbr H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S2/SvPas * C57BL/6J * CBA/J	normal nervous system phenotype	J:157532

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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