Mthfr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mthfr
methylenetetrahydrofolate reductase
MGI:106639

17 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mthfr^tm1Rzn/Mthfr⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal lipid homeostasis	J:67779
	increased circulating homocysteine level	J:67779
	microvesicular hepatic steatosis	J:67779
Mthfr^tm1Rzn/Mthfr⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl	increased circulating homocysteine level	J:150548
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ	abnormal blood homeostasis	J:165612
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ	increased circulating homocysteine level	J:165612
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal cerebellar granule layer morphology	J:67779
	abnormal lipid homeostasis	J:67779
	decreased body weight	J:67779
	delaminated Purkinje cell layer	J:67779
	delayed sexual maturation	J:67779
	exophthalmos	J:67779
	increased circulating homocysteine level	J:67779
	kinked tail	J:67779
	kyphosis	J:67779
	microvesicular hepatic steatosis	J:67779
	postnatal growth retardation	J:67779
	premature death	J:67779
	short tail	J:67779
	small cerebellum	J:67779
	sparse hair	J:67779
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl	normal homeostasis/metabolism phenotype	J:150548
	increased circulating homocysteine level	J:150548

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24