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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ly6e
lymphocyte antigen 6 family member E
MGI:106651
30 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ly6eem1(IMPC)Bay/Ly6e+
C57BL/6N-Ly6eem1(IMPC)Bay/Bay 		embryonic growth retardation J:211773
Ly6eem1(IMPC)Bay/Ly6eem1(IMPC)Bay
C57BL/6N-Ly6eem1(IMPC)Bay/Bay 		abnormal embryo size J:211773
abnormal placenta size J:211773
embryonic growth retardation J:211773
pale yolk sac J:211773
pallor J:211773
prenatal lethality J:211773
preweaning lethality, complete penetrance J:211773
Ly6etm1c(EUCOMM)Hmgu/Ly6etm1c(EUCOMM)Hmgu
Commd10Tg(Vav1-icre)A2Kio/Commd10+
B6.Cg-Ly6etm1c(EUCOMM)Hmgu Commd10Tg(Vav1-icre)A2Kio 		abnormal liver morphology J:291868
abnormal mononuclear cell morphology J:291868
decreased B cell number J:291868
decreased CD4-positive, alpha-beta T cell number J:291868
decreased dendritic cell number J:291868
decreased inflammatory response J:291868
decreased macrophage cell number J:291868
decreased neutrophil cell number J:291868
decreased NK cell number J:291868
hepatic necrosis J:291868
increased circulating alanine transaminase level J:291868
increased susceptibility to Coronaviridae infection J:291868
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:291868
pale liver J:291868
Ly6etm1Zmt/Ly6etm1Zmt
involves: 129S1/Sv 		abnormal adrenal cortex morphology J:73972
abnormal heart ventricle morphology J:73972
abnormal interventricular septum morphology J:73972
decreased noradrenaline level J:73972
dilated cardiomyopathy J:73972
dilated heart atrium J:73972
enlarged heart J:73972
failure of adrenal epinephrine secretion J:73972
lethality throughout fetal growth and development, complete penetrance J:73972
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory