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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Epcam
epithelial cell adhesion molecule
MGI:106653
38 phenotypes from 6 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal colon morphology J:195002
abnormal crypts of Lieberkuhn morphology J:195002
abnormal enterocyte morphology J:195002
abnormal intestinal epithelium morphology J:195002
abnormal intestinal mucosa morphology J:195002
abnormal intestine morphology J:195002
abnormal intestine physiology J:195002
internal hemorrhage J:195002
postnatal growth retardation J:195002
postnatal lethality, complete penetrance J:195002
slow postnatal weight gain J:195002
EpcamGt(RST556)Byg/EpcamGt(RST556)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal neural tube closure J:155941
abnormal placenta labyrinth morphology J:155941
abnormal thrombosis J:155941
decreased embryo size J:155941
decreased trophoblast giant cell number J:155941
delayed neural tube closure J:155941
embryonic growth arrest J:155941
embryonic lethality during organogenesis, complete penetrance J:155941
small placenta J:155941
Epcamtm1.1Mcu/Epcamtm1.1Mcu
Tg(CD207-cre)1Dhka/0
involves: 129 * C57BL/6 * C57BL/6J * SJL/J 		abnormal cell migration J:182665
abnormal Langerhans cell morphology J:182665
abnormal Langerhans cell physiology J:182665
increased susceptibility to type IV hypersensitivity reaction J:182665
Epcamtm1.2Hmd/Epcamtm1.2Hmd
involves: 129 * C57BL/6 		abnormal intestine physiology J:190580
lethality during fetal growth through weaning, incomplete penetrance J:190580
Epcamtm1.2Msiv/Epcamtm1.2Msiv
involves: C57BL/6 * FVB/N * SJL 		abnormal duodenum morphology J:210901
abnormal enterocyte physiology J:210901
abnormal enterocyte proliferation J:210901
abnormal ileum morphology J:210901
abnormal intestine morphology J:210901
abnormal intestine physiology J:210901
abnormal jejunum morphology J:210901
normal behavior/neurological phenotype J:210901
blunted small intestinal villi J:210901
decreased body size J:210901
intestinal edema J:210901
lethargy J:210901
postnatal growth retardation J:210901
postnatal lethality, complete penetrance J:210901
small intestinal inflammation J:210901
Epcamtm1Hmd/Epcamtm1Hmd
involves: 129 * C57BL/6 		abnormal intestinal mucosa morphology J:190580
diarrhea J:190580
intestinal hemorrhage J:190580
lethality during fetal growth through weaning, incomplete penetrance J:190580
postnatal growth retardation J:190580
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory