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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Adipoq
adiponectin, C1Q and collagen domain containing
MGI:106675
91 phenotypes from 7 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adipoqtm1b(KOMP)Wtsi/Adipoqtm1b(KOMP)Wtsi
C57BL/6N-Adipoqtm1b(KOMP)Wtsi/Tcp 		abnormal heart morphology J:211773
enlarged heart J:211773
Adipoqtm1b(KOMP)Wtsi/Adipoqtm1b(KOMP)Wtsi
C57BL/6NCrl-Adipoqtm1b(KOMP)Wtsi/Tcp 		decreased pulmonary ventilation J:211773
Adipoqtm1Chan/Adipoq+
B6.129-Adipoqtm1Chan 		abnormal leukocyte physiology J:122020
decreased circulating adiponectin level J:122020
increased leukocyte cell number J:122020
increased vascular endothelial cell adhesion J:122020
Adipoqtm1Chan/Adipoqtm1Chan
B6.129-Adipoqtm1Chan 		abnormal leukocyte physiology J:122020
abnormal nitric oxide homeostasis J:122020
decreased circulating adiponectin level J:122020
decreased fatty acid beta-oxidation J:79122
normal homeostasis/metabolism phenotype J:79122
increased leukocyte cell number J:122020
increased vascular endothelial cell adhesion J:122020
Adipoqtm1Chan/Adipoqtm1Chan
involves: 129S1/Sv * 129X1/SvJ 		abnormal lipid homeostasis J:138678
abnormal skeletal muscle fiber morphology J:138678
increased body weight J:138678
Adipoqtm1Chan/Adipoqtm1Chan
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		albuminuria J:136297
fused podocyte foot processes J:136297
oxidative stress J:136297
Adipoqtm1Far/Adipoqtm1Far
involves: 129S4/SvJae * C57BL/6J 		impaired glucose tolerance J:111346
increased body weight J:111346
increased circulating glucose level J:111346
increased liver triglyceride level J:111346
increased percent body fat/body weight J:111346
increased susceptibility to diet-induced hepatic steatosis J:111346
increased total body fat amount J:111346
Adipoqtm1Far/Adipoqtm1Far
involves: C57BL/6J 		impaired glucose tolerance J:111346
Adipoqtm1Ish/Adipoqtm1Ish
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal abdominal fat pad morphology J:199264
abnormal cardiovascular system morphology J:106599
abnormal cardiovascular system physiology J:106599
abnormal energy homeostasis J:199264
abnormal gas homeostasis J:199264
abnormal glucose homeostasis J:199264
abnormal hormone level J:199264
abnormal lipid level J:77479
abnormal osteoblast physiology J:199264
abnormal osteoclast morphology J:199264
abnormal skeleton morphology J:199264
abnormal skeleton physiology J:199264
abnormal urine homeostasis J:199264
abnormal vascular wound healing J:79350
abnormal vasodilation J:103106
abnormal white adipose tissue morphology J:199264
cardiac hypertrophy J:106599
congestive heart failure J:106599
decreased body weight J:199264
decreased bone mass J:199264
decreased bone mineral density J:199264
decreased bone ossification J:199264
decreased bone trabecula number J:199264
decreased food intake J:199264
decreased heart left ventricle muscle contractility J:106599
decreased heart rate J:199264
decreased insulin secretion J:199264
decreased osteoblast cell number J:199264
decreased systemic arterial blood pressure J:199264
decreased total fat pad weight J:199264
decreased trabecular bone volume J:199264
dilated heart left ventricle J:106599
hemorrhage J:106599
normal homeostasis/metabolism phenotype J:199264
hyperglycemia J:77479, J:103106
impaired glucose tolerance J:199264
increased adiponectin level J:199264
increased bone mass J:199264
increased bone mineral density J:199264
increased bone ossification J:199264
increased bone strength J:199264
increased carbon dioxide production J:199264
increased circulating adiponectin level J:199264
increased circulating free fatty acids level J:77479
increased circulating glucose level J:106599
increased circulating insulin level J:77479
increased circulating osteocalcin level J:199264
increased compact bone thickness J:199264
increased energy expenditure J:199264
increased noradrenaline level J:199264
increased osteoblast cell number J:199264
increased oxygen consumption J:199264
increased susceptibility to diet-induced obesity J:103106
increased susceptibility to induced morbidity/mortality J:106599
increased systemic arterial systolic blood pressure J:103106
increased trabecular bone volume J:199264
increased urine adrenaline level J:199264
insulin resistance J:77479
normal liver/biliary system phenotype J:199264
normal muscle phenotype J:199264
oxidative stress J:199264
pulmonary edema J:106599
pulmonary vascular congestion J:106599
normal skeleton phenotype J:199264
vascular restenosis J:79350
Adipoqtm1Pesch/Adipoqtm1Pesch
B6.129S7-Adipoqtm1Pesch 		abnormal inguinal fat pad morphology J:210480
abnormal respiratory electron transport chain J:210480
decreased susceptibility to induced hypothermia J:210480
increased core body temperature J:210480
increased energy expenditure J:210480
increased oxygen consumption J:210480
Adipoqtm1Pesch/Adipoqtm1Pesch
involves: 129S7/SvEvBrd 		abnormal gluconeogenesis J:107486
impaired glucose tolerance J:107486
Adipoqtm1Pesch/Adipoqtm1Pesch
involves: C57BL/6 		maternal effect J:219264
Adipoqtm1Tka/Adipoq+
involves: 129S4/SvJae * C57BL/6 		impaired glucose tolerance J:77876
insulin resistance J:77876
Adipoqtm1Tka/Adipoqtm1Tka
involves: 129S4/SvJae * C57BL/6 		abnormal vascular wound healing J:77876
impaired glucose tolerance J:77876
increased circulating triglyceride level J:77876
insulin resistance J:77876
Tg(APOE-Adipoq)#Kry/0
involves: 129 * C57BL/6J 		decreased bone mass J:199264
decreased bone ossification J:199264
decreased circulating osteocalcin level J:199264
decreased osteoblast cell number J:199264
increased circulating adiponectin level J:199264
increased trabecular bone volume J:199264
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory