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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zic2
zinc finger protein of the cerebellum 2
MGI:106679
90 phenotypes from 9 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Zic2em1Bend/Zic2+
involves: C57BL/6J 		curly tail J:199882
Zic2em2Bend/Zic2+
involves: C3H/HeH 		curly tail J:199882
Zic2em3Bend/Zic2+
involves: C3H/HeH 		curly tail J:199882
Zic2em4Bend/Zic2+
involves: C3H/HeH 		curly tail J:199882
Zic2em5Bend/Zic2+
involves: C3H/HeH 		curly tail J:199882
Zic2iso/Zic2iso
involves: C3H/HeH * C57BL/6 		abnormal heart ventricle morphology J:268103
abnormal hepatic vein connection J:268103
abnormal pancreas morphology J:268103
abnormal spleen morphology J:268103
abnormal spleen size J:268103
absent spleen J:268103
alobar holoprosencephaly J:268103
anophthalmia J:268103
atrial septal defect J:268103
curly tail J:268103
cyclopia J:268103
dextrocardia J:268103
double outlet right ventricle J:268103
exencephaly J:268103
heterotaxia J:268103
left sided inferior vena cava J:268103
mesocardia J:268103
ocular hypotelorism J:268103
right aortic arch J:268103
right atrial isomerism J:268103
right pulmonary isomerism J:268103
right-sided isomerism J:268103
right-sided stomach J:268103
spina bifida J:268103
ventricular septal defect J:268103
Zic2Ku/Zic2+
C3.CAnNCrl-Zic2Ku 		belly spot J:86841
curly tail J:86841
kinked tail J:86841
spina bifida J:86841
Zic2Ku/Zic2+
involves: BALB/c * C3H/HeN 		belly spot J:63816
curly tail J:63816
Zic2Ku/Zic2Ku
129S.CAnNCrl(C3)-Zic2Ku 		rostral body truncation J:238567
Zic2Ku/Zic2Ku
C3.CAnNCrl-Zic2Ku 		abnormal eye distance/ position J:138862
abnormal forebrain development J:138862
abnormal notochord morphology J:138862
abnormal prechordal plate morphology J:138862
abnormal primitive node morphology J:138862
curly tail J:138862
cyclopia J:138862
decreased neural crest cell number J:86841
decreased rhombomere 3 size J:86841
decreased rhombomere 5 size J:86841
delayed caudal neuropore closure J:86841
embryonic lethality during organogenesis, complete penetrance J:86841
exencephaly J:138862
hematoma J:86841
holoprosencephaly J:138862
incomplete rostral neuropore closure J:86841
increased ectoderm apoptosis J:138862
ocular hypotelorism J:138862
proboscis J:138862
spina bifida J:138862
Zic2m1Nisw/Zic2m1Nisw
129S1.B6-Zic2m1Nisw 		abnormal enteric nervous system morphology J:214510
abnormal enteric neural crest cell morphology J:214510
abnormal enteric neuron morphology J:214510
abnormal intestine morphology J:214510
abnormal intestine physiology J:214510
abnormal neurite morphology J:214510
exencephaly J:169832, J:214510
perinatal lethality, complete penetrance J:214510
spina bifida J:214510
Zic2tm1Jaru/Zic2+
B6.129S4-Zic2tm1Jaru 		normal behavior/neurological phenotype J:72342
decreased prepulse inhibition J:72342
increased startle reflex J:72342
Zic2tm1Jaru/Zic2+
involves: 129S4/SvJae * C57BL/6J 		abnormal amygdala morphology J:174352
abnormal cerebral hemisphere morphology J:174352
abnormal spatial learning J:174352
abnormal spatial working memory J:174352
normal behavior/neurological phenotype J:174352
decreased aggression towards mice J:174352
decreased brain size J:174352
decreased corpus callosum size J:174352
decreased locomotor activity J:174352
decreased neuron number J:174352
enlarged lateral ventricles J:174352
hyperactivity J:174352
impaired contextual conditioning behavior J:174352
impaired cued conditioning behavior J:174352
thin cerebral cortex J:174352
Zic2tm1Jaru/Zic2tm1Jaru
involves: 129S4/SvJae * C57BL/6 		abnormal autopod rotation J:60644
abnormal brain development J:60644
abnormal cerebral cortex morphology J:60644
abnormal dorsal root ganglion morphology J:60644
abnormal forebrain development J:60644
abnormal limb bone morphology J:60644
abnormal nervous system development J:60644
abnormal neural fold formation J:60644
abnormal neural plate morphology J:60644
abnormal neural tube morphology J:60644
abnormal olfactory bulb morphology J:60644
abnormal roof plate morphology J:60644
abnormal spinal cord dorsal horn morphology J:60644
abnormal telencephalon development J:60644
abnormal vertebral arch morphology J:60644
anencephaly J:60644
curly tail J:60644
exencephaly J:60644
fused carpal bones J:60644
fused metacarpal bones J:60644
fused metatarsal bones J:60644
fused tarsal bones J:60644
fusion of vertebral arches J:60644
hindlimb paralysis J:60644
holoprosencephaly J:60644
microcephaly J:60644
postnatal lethality, complete penetrance J:60644
spina bifida J:60644
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory