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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hccs
holocytochrome c synthetase
MGI:106911
27 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arhgap6/Hccs/Mid1tm1Hzo/Y
involves: 129S7/SvEvBrd 		no abnormal phenotype detected J:80528
Arhgap6/Hccs/Mid1tm1Hzo/Hccs+
Tg(EIIa-cre)C5379Lmgd/?
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		prenatal lethality, complete penetrance J:80528
Arhgap6/Hccs/Mid1tm1Hzo/Arhgap6/Hccs/Mid1tm1Hzo
involves: 129S7/SvEvBrd 		no abnormal phenotype detected J:80528
Arhgap6/Hccs/Mid1tm1Hzo/Arhgap6/Hccs/Mid1tm1Hzo
Tg(EIIa-cre)C5379Lmgd/?
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		abnormal embryo development J:80528
abnormal gastrulation J:80528
embryonic growth retardation J:80528
prenatal lethality, complete penetrance J:80528
Arhgap6/Hccs/Mid1tm1Hzo/Y
Tg(EIIa-cre)C5379Lmgd/?
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		abnormal embryo development J:80528
abnormal gastrulation J:80528
embryonic growth retardation J:80528
prenatal lethality, complete penetrance J:80528
Hccstm1Tcc/Hccs+
Nkx2-5tm2(cre)Rph/Nkx2-5+
involves: 129S1/Sv 		abnormal atrial thrombosis J:143285
abnormal fetal cardiomyocyte mitochondrial morphology J:143285
abnormal myocardial fiber physiology J:143285
abnormal myocardium layer morphology J:143285
abnormal respiratory electron transport chain J:143285
atrioventricular block J:143285
bundle branch block J:143285
cardiac interstitial fibrosis J:143285
dilated cardiomyopathy J:143285
dilated heart atrium J:143285
dilated heart left ventricle J:143285
dilated heart right ventricle J:143285
enlarged heart J:143285
premature death J:143285
sinoatrial block J:143285
thick ventricular wall J:143285
Hccstm1Tcc/Hccs+
Nkx2-5tm2(cre)Rph/Nkx2-5+
Tg(CAG-EGFP)D4Nagy/0
Tg(Hmgcr-lacZ)H253Sest/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal fetal cardiomyocyte morphology J:143285
abnormal fetal cardiomyocyte proliferation J:143285
decreased fetal cardiomyocyte size J:143285
Hccstm1Tcc/Hccstm1Tcc
Nkx2-5tm2(cre)Rph/Nkx2-5+
involves: 129S1/Sv 		embryonic lethality during organogenesis, incomplete penetrance J:143285
Hccstm1Tcc/Y
Nkx2-5tm2(cre)Rph/Nkx2-5+
involves: 129S1/Sv 		abnormal fetal cardiomyocyte mitochondrial morphology J:143285
abnormal fetal cardiomyocyte morphology J:143285
abnormal respiratory electron transport chain J:143285
decreased cardiac muscle glycogen level J:143285
decreased fetal cardiomyocyte proliferation J:143285
embryonic lethality during organogenesis, incomplete penetrance J:143285
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory