Aff3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aff3
AF4/FMR2 family, member 3
MGI:106927

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aff3^em1Andg/Aff3⁺ involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1	prenatal lethality	J:317476
Aff3^em1Andg/Aff3^em1Andg chimera involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1	abnormal craniofacial morphology	J:317476
	abnormal fibula morphology	J:317476
	abnormal intestine morphology	J:317476
	abnormal nervous system physiology	J:317476
	abnormal pelvic girdle bone morphology	J:317476
	abnormal tibia morphology	J:317476
	decreased fetal size	J:317476
	decreased length of long bones	J:317476
	delayed bone ossification	J:317476
	polydactyly	J:317476
Aff3^em1Xen/Aff3⁺ involves: C57BL/6N	prenatal lethality	J:317476
Aff3^{tm1a(EUCOMM)Wtsi}/Aff3⁺ C57BL/6N-Aff3^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal vertebral arch morphology	J:211773
Aff3^{tm1a(EUCOMM)Wtsi}/Aff3^{tm1a(EUCOMM)Wtsi} C57BL/6N-Aff3^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal incisor morphology	J:211773
	abnormal snout morphology	J:211773
	abnormal tooth morphology	J:211773
	abnormal vertebral arch morphology	J:211773
	decreased circulating fructosamine level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased corpus callosum size	J:317476
	decreased grip strength	J:211773
	enlarged lateral ventricles	J:317476
	fusion of vertebral arches	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating chloride level	J:211773
	vertebral transformation	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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