Hmx3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hmx3
H6 homeobox 3
MGI:107160

37 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hmx3/Hmx2^tm3Tlu/Hmx3/Hmx2^tm3Tlu either: (involves: 129) or (involves: 129 * C57BL/6J)	abnormal endolymphatic duct morphology	J:92940
	abnormal hypothalamus secretion	J:92940
	abnormal membranous labyrinth morphology	J:92940
	absent semicircular canals	J:92940
	decreased circulating growth hormone level	J:92940
	decreased vestibular hair cell number	J:92940
	impaired balance	J:92940
	muscle spasm	J:92940
	postnatal growth retardation	J:92940
	postnatal lethality, complete penetrance	J:92940
	small adenohypophysis	J:92940
	small pituitary gland	J:92940
	utricular degeneration	J:92940
	vestibular saccular degeneration	J:92940
Hmx3^tm1Ebo/Hmx3⁺ either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)	no abnormal phenotype detected	J:45576
Hmx3^tm1Ebo/Hmx3^tm1Ebo either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)	abnormal inner ear morphology	J:45576
	abnormal posterior semicircular canal morphology	J:45576
	absent inner ear vestibule	J:45576
	absent lateral semicircular canal	J:45576
	absent posterior semicircular canal	J:45576
	circling	J:45576
	decreased posterior semicircular canal size	J:45576
	decreased superior semicircular canal size	J:45576
	hyperactivity	J:45576
	postnatal growth retardation	J:45576
Hmx3^tm1Ebo/Hmx3^tm1Ebo involves: 129S4/SvJae	abnormal semicircular canal morphology	J:78406
Hmx3^tm1Tlu/Hmx3^tm1Tlu involves: 129 * C57BL/6J	abnormal crista ampullaris morphology	J:46379
	abnormal decidualization	J:46379
	abnormal lateral semicircular canal morphology	J:46379
	abnormal otolith organ morphology	J:46379
	abnormal utricle morphology	J:46379
	abnormal vestibular labyrinth morphology	J:46379
	abnormal vestibular saccule morphology	J:46379
	circling	J:46379
	failure of embryo implantation	J:46379
	hyperactivity	J:46379
	postnatal lethality, incomplete penetrance	J:46379
	reduced female fertility	J:46379
	utricular macular degeneration	J:46379
	vestibular saccular macula degeneration	J:46379
Hmx3^tm2Tlu/Hmx3^tm2Tlu involves: 129 * C57BL/6J	abnormal crista ampullaris morphology	J:46379
	abnormal decidualization	J:46379
	abnormal lateral semicircular canal morphology	J:46379
	abnormal otolith organ morphology	J:46379
	abnormal utricle morphology	J:46379
	abnormal vestibular labyrinth morphology	J:46379
	abnormal vestibular saccule morphology	J:46379
	circling	J:46379
	failure of embryo implantation	J:46379
	hyperactivity	J:46379
	postnatal lethality, incomplete penetrance	J:46379
	reduced female fertility	J:46379
	utricular macular degeneration	J:46379
	vestibular saccular macula degeneration	J:46379

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24